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Elismetrep

Name: Elismetrep
Brand: TargetMol
SKU: T27253
Price: 126 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T27253Cas No. 1400699-64-0

Alias MT-8554, MT8554, MT 8554

Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.

Elismetrep

🥰Excellent

Purity: 99.93%

Catalog No. T27253Alias MT-8554, MT8554, MT 8554Cas No. 1400699-64-0

Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.

Pack Size	Price	Availability
1 mg	$126	In Stock
5 mg	$313	In Stock
10 mg	$490	In Stock
25 mg	$977	In Stock
50 mg	$1,460	In Stock
100 mg	$1,970	In Stock
200 mg	$2,660	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.93%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.
Synonyms	MT-8554, MT8554, MT 8554

Chemical Properties

Molecular Weight	542.53
Formula	C₂₇H₂₁F₃N₂O₅S
Cas No.	1400699-64-0
Smiles	O=C(O)C1=CC=C(C=C1)S(=O)(=O)N(C=2N=CC3=CC=CC=C3C2C4CC4)CC5=CC=C(OC(F)(F)F)C=C5
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (147.46 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8432 mL	9.2161 mL	18.4322 mL	92.1608 mL
5 mM	0.3686 mL	1.8432 mL	3.6864 mL	18.4322 mL
10 mM	0.1843 mL	0.9216 mL	1.8432 mL	9.2161 mL
20 mM	0.0922 mL	0.4608 mL	0.9216 mL	4.6080 mL
50 mM	0.0369 mL	0.1843 mL	0.3686 mL	1.8432 mL
100 mM	0.0184 mL	0.0922 mL	0.1843 mL	0.9216 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc