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Anti-PI 3 Kinase Class 3 Antibody (2W658)

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Catalog No. TMAC-03286

Anti-PI 3 Kinase Class 3 Antibody (2W658) is a Rabbit antibody targeting PI 3 Kinase Class 3. Anti-PI 3 Kinase Class 3 Antibody (2W658) can be used in WB,IHC.

Anti-PI 3 Kinase Class 3 Antibody (2W658)

Anti-PI 3 Kinase Class 3 Antibody (2W658)

😃Good
Catalog No. TMAC-03286
Anti-PI 3 Kinase Class 3 Antibody (2W658) is a Rabbit antibody targeting PI 3 Kinase Class 3. Anti-PI 3 Kinase Class 3 Antibody (2W658) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-PI 3 Kinase Class 3 Antibody (2W658) is a Rabbit antibody targeting PI 3 Kinase Class 3. Anti-PI 3 Kinase Class 3 Antibody (2W658) can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPhosphatidylinositol 3-kinases (PI3Ks) phosphorylate the 3' OH position of the inositol ring of inositol lipids. PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase, class III), is a member of the PI3/PI4-kinase family. It is ubiquitously expressed with predominant expression in skeletal muscle and is believed to participate in endosome to lysosome transport, multivesicular body formation, autophagy and retrograde endosome to Golgi transport. PI 3-kinase p100 is the catalytic subunit of class III PI3Ks and forms a heterodimer with p150, a regulatory subunit of class 3 PI3Ks. PI 3-kinase p100 exclusively phosphorylates phosphatidylinositol to produce PtdIns3P. Unlike class I PI3Ks, whose activities are enhanced in the presence of magnesium, PI 3-kinase p100 activity is enhanced by manganese. Its activity can also be regulated by nutrients, suggesting an important role of PI-3 kinase p100 in the regulation of mTOR protein synthesis and autophagy.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
48800
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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