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Anti-Cytokeratin 8 Antibody (5G219)
(Synonyms: KO, K8, K2C8, Cytokeratin8, CYK8, CK-8, CK8, CARD2) Copy Product Info
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Synonyms: KO, K8, K2C8, Cytokeratin8, CYK8, CK-8, CK8, CARD2
Catalog No. TMAB-00533 Copy Product Info
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Anti-Cytokeratin 8 Antibody (5G219) is a Mouse antibody targeting Cytokeratin 8. Anti-Cytokeratin 8 Antibody (5G219) can be used in FCM,IF,IHC-Fr,IHC-P.
Anti-Cytokeratin 8 Antibody
(5G219)
(5G219)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Cytokeratin 8 Antibody (5G219) is a Mouse antibody targeting Cytokeratin 8. Anti-Cytokeratin 8 Antibody (5G219) can be used in FCM,IF,IHC-Fr,IHC-P. |
| Synonyms | KO, K8, K2C8, Cytokeratin8, CYK8, CK-8, CK8, CARD2 |
| Ig Type | IgG |
| Clone | 5G219 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:200-800; FCM: 1ug/Test |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix. |
| Tissue Specificity | Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]. |
| Immunogen | Recombinant Protein: human CK8 |
| Antigen Species | Human |
| Gene Name | KRT8 |
| Gene ID | |
| Protein Name | Keratin, type II cytoskeletal 8 |
| Uniprot ID | |
| Biology Area | Cytokeratins |
| Function | Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
| Molecular Weight | Theoretical: 53 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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