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FSH Beta Protein, Human, Recombinant (His)

Catalog No. TMPY-00091
Synonyms: HH24, FSH β, follicle stimulating hormone, β polypeptide, follicle stimulating hormone, beta polypeptide

Follicle-stimulating hormone (FSH) is a gonadotrope-derived heterodimeric glycoprotein. FSH plays an essential role in processes involved in human reproduction, including spermatogenesis and the ovarian cycle. FSHB represents a conservative vertebrate gene with a unique function and it is located in a structurally stable gene-poor region. Polymorphisms in the follicle stimulating hormone beta subunit (FSHB) and follicle stimulating hormone receptor (FSHR) genes might disturb normal spermatogenesis and affect male reproductive ability. The FSHB -211G<T genotype is a key determinant in the regulation of gonadotropins in different reproductive-endocrine pathopyhsiologies.

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FSH Beta Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
50 μg 5 days $ 700.00
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Biological Description
Technical Params
Product Properties
Description Follicle-stimulating hormone (FSH) is a gonadotrope-derived heterodimeric glycoprotein. FSH plays an essential role in processes involved in human reproduction, including spermatogenesis and the ovarian cycle. FSHB represents a conservative vertebrate gene with a unique function and it is located in a structurally stable gene-poor region. Polymorphisms in the follicle stimulating hormone beta subunit (FSHB) and follicle stimulating hormone receptor (FSHR) genes might disturb normal spermatogenesis and affect male reproductive ability. The FSHB -211G>T genotype is a key determinant in the regulation of gonadotropins in different reproductive-endocrine pathopyhsiologies.
Species Human
Expression System HEK293
Tag His
Accession Number A0A0F7RQE8
Synonyms HH24, FSH β, follicle stimulating hormone, β polypeptide, follicle stimulating hormone, beta polypeptide
Construction A DNA sequence encoding the human FSHB (NP_000501.1) (Met1-Glu129) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity > 90 % as determined by SDS-PAGE.
Molecular Weight 13.9 kDa (predicted)
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Formulation Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Follicle-stimulating hormone (FSH) is a gonadotrope-derived heterodimeric glycoprotein. FSH plays an essential role in processes involved in human reproduction, including spermatogenesis and the ovarian cycle. FSHB represents a conservative vertebrate gene with a unique function and it is located in a structurally stable gene-poor region. Polymorphisms in the follicle stimulating hormone beta subunit (FSHB) and follicle stimulating hormone receptor (FSHR) genes might disturb normal spermatogenesis and affect male reproductive ability. The FSHB -211G>T genotype is a key determinant in the regulation of gonadotropins in different reproductive-endocrine pathopyhsiologies.

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Keywords

FSH Beta Protein, Human, Recombinant (His) HH24 FSH β follicle stimulating hormone, β polypeptide HH 24 follicle stimulating hormone, beta polypeptide HH-24 follicle stimulating hormone, b polypeptide recombinant recombinant-proteins proteins protein

 

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