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Anti-BMP-7 Antibody (7G538)

😃Good
Catalog No. TMAY-00232
Alias Osteogenic protein 1, OP-1, OP1, Eptotermin alfa, Bone morphogenetic protein 7, BMP7

Anti-BMP-7 Antibody (7G538) is a Mouse antibody targeting BMP-7. Anti-BMP-7 Antibody (7G538) can be used in ELISA.

Anti-BMP-7 Antibody (7G538)

Anti-BMP-7 Antibody (7G538)

😃Good
Catalog No. TMAY-00232Alias Osteogenic protein 1, OP-1, OP1, Eptotermin alfa, Bone morphogenetic protein 7, BMP7
Anti-BMP-7 Antibody (7G538) is a Mouse antibody targeting BMP-7. Anti-BMP-7 Antibody (7G538) can be used in ELISA.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-BMP-7 Antibody (7G538) is a Mouse antibody targeting BMP-7. Anti-BMP-7 Antibody (7G538) can be used in ELISA.
AliasOsteogenic protein 1, OP-1, OP1, Eptotermin alfa, Bone morphogenetic protein 7, BMP7
Ig Type
Monoclonal Mouse IgG1
Clone
7G538
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP-7 (rh BMP-7; NP_001710.1; Ser 293-His 431). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundBMP-7 (Bone morphogenetic protein 7), also known as osteogenic protein 1 (OP-1), is a bone morphogenetic protein which belongs to the TGF-β superfamily. OP-1 is expressed in the brain, kidneys and bladder. BMP-7 may be involved in bone homeostasis. Osteogenic protein 1 plays a key role in the transformation of mesenchymal cells into bone and cartilage. The phosphorylation of SMAD1 and SMAD5 can be induced by BMP-7, which in turn induce transcription of numerous osteogenic genes. BMP-7 treatment can also induce all of the genetic markers of osteoblast differentiation in many cell types. The expression of BMP-7 causes ventral phenotypes while its complete inhibition creates a dorsal phenotype. Human recombinant BMP-7 protein can be used to aid in the fusion of vertebral bodies to prevent neurologic trauma. It also functions in the treatment of tibial non-union, frequently in cases where a bone graft has failed. It is found that BMP7 has the potential for treatment of chronic kidney disease.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human BMP-7 protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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