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Anti-BMP-7 Antibody (7G538)
😃Good
Catalog No. TMAY-00232
Alias Osteogenic protein 1, OP-1, OP1, Eptotermin alfa, Bone morphogenetic protein 7, BMP7
Anti-BMP-7 Antibody (7G538) is a Mouse antibody targeting BMP-7. Anti-BMP-7 Antibody (7G538) can be used in ELISA.
Anti-BMP-7 Antibody (7G538)
Anti-BMP-7 Antibody (7G538)
😃Good
Catalog No. TMAY-00232Alias Osteogenic protein 1, OP-1, OP1, Eptotermin alfa, Bone morphogenetic protein 7, BMP7
Anti-BMP-7 Antibody (7G538) is a Mouse antibody targeting BMP-7. Anti-BMP-7 Antibody (7G538) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | Osteogenic protein 1, OP-1, OP1, Eptotermin alfa, Bone morphogenetic protein 7, BMP7 |
| Ig Type | Mouse IgG1 |
| Clone | 7G538 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP-7 (rh BMP-7; NP_001710.1; Ser 293-His 431). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | BMP-7 (Bone morphogenetic protein 7), also known as osteogenic protein 1 (OP-1), is a bone morphogenetic protein which belongs to the TGF-β superfamily. OP-1 is expressed in the brain, kidneys and bladder. BMP-7 may be involved in bone homeostasis. Osteogenic protein 1 plays a key role in the transformation of mesenchymal cells into bone and cartilage. The phosphorylation of SMAD1 and SMAD5 can be induced by BMP-7, which in turn induce transcription of numerous osteogenic genes. BMP-7 treatment can also induce all of the genetic markers of osteoblast differentiation in many cell types. The expression of BMP-7 causes ventral phenotypes while its complete inhibition creates a dorsal phenotype. Human recombinant BMP-7 protein can be used to aid in the fusion of vertebral bodies to prevent neurologic trauma. It also functions in the treatment of tibial non-union, frequently in cases where a bone graft has failed. It is found that BMP7 has the potential for treatment of chronic kidney disease. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human BMP-7 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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