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Anti-Phospho-IRF3 (S386) Antibody (8Z898)

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Catalog No. TMAC-03230

Anti-Phospho-IRF3 (S386) Antibody (8Z898) is a Rabbit antibody targeting Phospho-IRF3 (S386). Anti-Phospho-IRF3 (S386) Antibody (8Z898) can be used in WB,ICC/IF.

Anti-Phospho-IRF3 (S386) Antibody (8Z898)

Anti-Phospho-IRF3 (S386) Antibody (8Z898)

😃Good
Catalog No. TMAC-03230
Anti-Phospho-IRF3 (S386) Antibody (8Z898) is a Rabbit antibody targeting Phospho-IRF3 (S386). Anti-Phospho-IRF3 (S386) Antibody (8Z898) can be used in WB,ICC/IF.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-IRF3 (S386) Antibody (8Z898) is a Rabbit antibody targeting Phospho-IRF3 (S386). Anti-Phospho-IRF3 (S386) Antibody (8Z898) can be used in WB,ICC/IF.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundInterferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γ p48 and IFN consensus sequence-binding protein (ICSBP).
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human IRF3 around the phosphorylation site of Ser386
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 47 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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