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Anti-Phospho-IRF3 (Ser386) Antibody (8Z898) (Synonyms: p-IRF3 (Ser386), p-IRF3 (S386), IRF3 (p-Ser386), IRF3 ...)
Catalog No. TMAC-03230 Copy Product Info
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Anti-Phospho-IRF3 (Ser386) Antibody (8Z898) is a Rabbit antibody targeting Phospho-IRF3 (Ser386). Anti-Phospho-IRF3 (Ser386) Antibody (8Z898) can be used in ICC/IF,WB.
Anti-Phospho-IRF3 (Ser386) Antibody (8Z898)
Copy Product Info🥰Excellent
Catalog No. TMAC-03230
Synonyms p-IRF3 (Ser386), p-IRF3 (S386), IRF3 (p-Ser386), IRF3 (p-S386)
Anti-Phospho-IRF3 (Ser386) Antibody (8Z898) is a Rabbit antibody targeting Phospho-IRF3 (Ser386). Anti-Phospho-IRF3 (Ser386) Antibody (8Z898) can be used in ICC/IF,WB.
Anti-Phospho-IRF3
(Ser386) Antibody
(8Z898)
(Ser386) Antibody
(8Z898)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-IRF3 (Ser386) Antibody (8Z898) is a Rabbit antibody targeting Phospho-IRF3 (Ser386). Anti-Phospho-IRF3 (Ser386) Antibody (8Z898) can be used in ICC/IF,WB. |
| Synonyms | p-IRF3 (Ser386), p-IRF3 (S386), IRF3 (p-Ser386), IRF3 (p-S386) |
| Ig Type | IgG |
| Clone | 8Z898 |
| Reactivity | Human |
| Verified Activity | 1. ICC staining Phospho-IRF3 (S386) in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 2. Western blot analysis of Phospho-IRF3 (S386) expression in PC-3 cell lysate. 3. Western blot analysis of Phospho-IRF3 (S386) expression in MCF7 cell lysate.    |
| Application | |
| Recommended Dose | WB: 1:1000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γ p48 and IFN consensus sequence-binding protein (ICSBP). |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human IRF3 around the phosphorylation site of Ser386 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 47 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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