Powder: -20°C for 3 years | In solvent: -80°C for 1 year
USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D. USP8-IN-2 is a potential compound for the treatment of cancer and viral infections.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 447.00 | |
10 mg | In stock | $ 659.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,380.00 | |
100 mg | In stock | $ 1,890.00 | |
500 mg | In stock | $ 3,790.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 498.00 |
Description | USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D. USP8-IN-2 is a potential compound for the treatment of cancer and viral infections. |
In vitro | USP8-IN-3 inhibits the proliferation of H1957 cells, with a GI50 of 24.93 μM[1]. |
Molecular Weight | 444.9 |
Formula | C19H20ClF3N4OS |
CAS No. | 2477651-11-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (61.81 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
USP8-IN-2 2477651-11-7 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB inhibitor inhibit