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Metipranolol hydrochloride

Name: Metipranolol hydrochloride
Brand: TargetMol
SKU: T16066
Rating: 4.5 (1 reviews)

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Catalog No. T16066Cas No. 36592-77-5

Metipranolol hydrochloride is a non-selective β-adrenergic receptor blocking agent.

Metipranolol hydrochloride

😃Good

Catalog No. T16066Cas No. 36592-77-5

Metipranolol hydrochloride is a non-selective β-adrenergic receptor blocking agent.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$77	7-10 days	7-10 days
25 mg	$232	7-10 days	7-10 days
50 mg	$347	7-10 days	7-10 days
100 mg	$521	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Metipranolol hydrochloride is a non-selective β-adrenergic receptor blocking agent.
In vitro	Metipranolol is administered systemically to treat arterial hypertension and is applied topically for managing glaucoma.

Chemical Properties

Molecular Weight	345.86
Formula	C₁₇H₂₈ClNO₄
Cas No.	36592-77-5
Smiles	Cl.CC(C)NCC(O)COc1cc(C)c(OC(C)=O)c(C)c1C
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (289.13 mM), Sonication is recommended.

H2O: 100 mg/mL (289.13 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (9.54 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.8913 mL	14.4567 mL	28.9134 mL	144.5672 mL
5 mM	0.5783 mL	2.8913 mL	5.7827 mL	28.9134 mL
10 mM	0.2891 mL	1.4457 mL	2.8913 mL	14.4567 mL
20 mM	0.1446 mL	0.7228 mL	1.4457 mL	7.2284 mL
50 mM	0.0578 mL	0.2891 mL	0.5783 mL	2.8913 mL
100 mM	0.0289 mL	0.1446 mL	0.2891 mL	1.4457 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc