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Anti-TMSB4X Polyclonal Antibody
😃Good
Catalog No. TMAB-01868
Alias TMSB4X, TMSB4, Thymosin beta-4, THYB4, TB4X, T beta-4, Fx
Anti-TMSB4X Polyclonal Antibody is a Rabbit antibody targeting TMSB4X. Anti-TMSB4X Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
Anti-TMSB4X Polyclonal Antibody
Anti-TMSB4X Polyclonal Antibody
😃Good
Catalog No. TMAB-01868Alias TMSB4X, TMSB4, Thymosin beta-4, THYB4, TB4X, T beta-4, Fx
Anti-TMSB4X Polyclonal Antibody is a Rabbit antibody targeting TMSB4X. Anti-TMSB4X Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-TMSB4X Polyclonal Antibody is a Rabbit antibody targeting TMSB4X. Anti-TMSB4X Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P. |
| Synonyms | TMSB4X, TMSB4, Thymosin beta-4, THYB4, TB4X, T beta-4, Fx |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Thymosin beta 4) Polyclonal Antibody, Unconjugated (TMAB-01868) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.  |
| Application | |
| Recommended Dose | IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton. |
| Tissue Specificity | Originally found in thymus but it is widely distributed in many tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Proteins in the thymosin beta family are highly conserved polar peptides that bind monomeric Actin and thereby inhibit Actin polymerization. These proteins act as the main intracellular G-Actin sequestering peptides. The most abundant thymosin beta family member in mammalian cells and tissues is thymosin beta-4 (Tbeta-4), also designated Seraspenide. T beta-4 participates in several cellular events including cancerogenesis, apoptosis, angiogenesis, blood coagulation and would healing. Specifically, T beta-4 promotes cell migration and adhesion, accelerates wound healing and reduces inflammation, and becomes upregulated in a wide variety of human carcinomas. Due to the effects of T beta-4 in these events, it may become a protein of significant biological and pharmaceutical relevance. |
| Immunogen | KLH conjugated synthetic peptide: human Thymosin beta 4 |
| Antigen Species | Human |
| Gene Name | TMSB4X |
| Gene ID | |
| Protein Name | Thymosin beta-4 |
| Uniprot ID | |
| Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase. |
| Molecular Weight | Theoretical: 4.8 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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