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Propranolol-d7 hydrochloride (Synonyms: Propranolol D7 hydrochloride)

Name: Propranolol-d7 hydrochloride
Brand: TargetMol
SKU: T12550
Rating: 4.5 (1 reviews)

Catalog No. T12550 Copy Product Info

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Propranolol-d7 hydrochloride is a deuterated isotope marker of Propranolol, which can be used for isotope tracing. Propranolol is a non-selective beta-blocker used for hypertension research

Propranolol-d7 hydrochloride

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Catalog No. T12550

Synonyms Propranolol D7 hydrochloride

Propranolol-d7 hydrochloride is a deuterated isotope marker of Propranolol, which can be used for isotope tracing. Propranolol is a non-selective beta-blocker used for hypertension research

Cas No. 1613439-56-7

Pack Size	Price	USA Stock	Global Stock	Quantity
1 mg	$179	5 days	5 days
5 mg	$455	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	Propranolol-d7 hydrochloride is a deuterated isotope marker of Propranolol, which can be used for isotope tracing. Propranolol is a non-selective beta-blocker used for hypertension research
Targets&IC50	β-adrenoceptor:12 nM
In vitro	Propranolol-d7 hydrochloride's parent shows high affinity for beta1-AR (Ki=1.8 nM) and beta2-AR (Ki=0.8 nM) [1][3].
Synonyms	Propranolol D7 hydrochloride

Chemical Properties

Molecular Weight	302.85
Formula	C₁₆H₂₂ClNO₂
Cas No.	1613439-56-7
Smiles	O(CC(CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])O)C=1C2=C(C=CC1)C=CC=C2.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (264.16 mM), Sonication is recommmended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3020 mL	16.5098 mL	33.0196 mL	165.0982 mL
5 mM	0.6604 mL	3.3020 mL	6.6039 mL	33.0196 mL
10 mM	0.3302 mL	1.6510 mL	3.3020 mL	16.5098 mL
20 mM	0.1651 mL	0.8255 mL	1.6510 mL	8.2549 mL
50 mM	0.0660 mL	0.3302 mL	0.6604 mL	3.3020 mL
100 mM	0.0330 mL	0.1651 mL	0.3302 mL	1.6510 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc