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Perlolyrine

Name: Perlolyrine
Brand: TargetMol
SKU: TN6548
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN6548Cas No. 29700-20-7

Alias Tribulusterine

Perlolyrine (Tribulusterine) is a naturally occurring alkaloid with molecular docking capacity (-5.73 to -6.59 kJ/mol) with MAPK1, MAPK14, and SRC, with potential anticancer and anti-inflammatory effects.

Perlolyrine

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Purity: 99.62%

Catalog No. TN6548Alias TribulusterineCas No. 29700-20-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	In Stock	In Stock
5 mg	$117	In Stock	In Stock
10 mg	$187	In Stock	In Stock
25 mg	$376	In Stock	In Stock
50 mg	$591	-	In Stock
100 mg	$969	-	In Stock
200 mg	$1,280	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.62%

Appearance:Solid

Color:Yellow

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Perlolyrine (Tribulusterine) is a naturally occurring alkaloid with molecular docking capacity (-5.73 to -6.59 kJ/mol) with MAPK1, MAPK14, and SRC, with potential anticancer and anti-inflammatory effects.
In vitro	Perlolyrine inhibits α-MSH-induced melanogenesis in B16F10 mouse melanoma cells in a dose-dependent manner (5-25 μM, 48 h). At 25 μM, Perlolyrine reduces melanin content by over 50% without affecting cell viability. Perlolyrine also suppresses the expression of melanogenesis-related genes such as MITF, tyrosinase, and TRP-1[1].
Synonyms	Tribulusterine

Chemical Properties

Molecular Weight	264.28
Formula	C₁₆H₁₂N₂O₂
Cas No.	29700-20-7
Smiles	OCC=1OC(=CC1)C2=NC=CC=3C4=CC=CC=C4NC23
Relative Density.	1.382 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (302.71 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7839 mL	18.9193 mL	37.8387 mL	189.1933 mL
5 mM	0.7568 mL	3.7839 mL	7.5677 mL	37.8387 mL
10 mM	0.3784 mL	1.8919 mL	3.7839 mL	18.9193 mL
20 mM	0.1892 mL	0.9460 mL	1.8919 mL	9.4597 mL
50 mM	0.0757 mL	0.3784 mL	0.7568 mL	3.7839 mL
100 mM	0.0378 mL	0.1892 mL	0.3784 mL	1.8919 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc