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Anti-GABRP Polyclonal Antibody
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Catalog No. TMAB-00731
Alias Gamma-aminobutyric acid receptor subunit pi, GABRP, GABA(A) receptor subunit pi (GABAAR subunit pi)
Anti-GABRP Polyclonal Antibody is a Rabbit antibody targeting GABRP. Anti-GABRP Polyclonal Antibody can be used in WB.
Anti-GABRP Polyclonal Antibody
Anti-GABRP Polyclonal Antibody
😃Good
Catalog No. TMAB-00731Alias Gamma-aminobutyric acid receptor subunit pi, GABRP, GABA(A) receptor subunit pi (GABAAR subunit pi)
Anti-GABRP Polyclonal Antibody is a Rabbit antibody targeting GABRP. Anti-GABRP Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-GABRP Polyclonal Antibody is a Rabbit antibody targeting GABRP. Anti-GABRP Polyclonal Antibody can be used in WB. |
| Synonyms | Gamma-aminobutyric acid receptor subunit pi, GABRP, GABA(A) receptor subunit pi (GABAAR subunit pi) |
| Reactivity | Mouse (predicted:Human,Rat,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | Sample: Kidney (Mouse) Lysate at 40 μg Primary: Anti-GABA A receptor pi (TMAB-00731) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kDa Observed band size: 49 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell junction; synapse; postsynaptic cell membrane. Cell membrane. |
| Tissue Specificity | Most abundant in the uterus, also expressed in lung, thymus and prostate. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. |
| Immunogen | KLH conjugated synthetic peptide: human GABRP/GABA A receptor pi |
| Antigen Species | Human |
| Gene Name | GABRP |
| Gene ID | |
| Protein Name | gamma-aminobutyric acid receptor subunit pi |
| Uniprot ID | |
| Biology Area | More GPCR,GABA Receptors,GABA |
| Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. |
| Molecular Weight | Theoretical: 49 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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