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TRAP-6

Name: TRAP-6
Brand: TargetMol
SKU: T7625
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7625Cas No. 141136-83-6

Alias Thrombin Receptor Activator Peptide 6, PAR-1 agonist peptide

TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).

TRAP-6

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Catalog No. T7625Alias Thrombin Receptor Activator Peptide 6, PAR-1 agonist peptideCas No. 141136-83-6

TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$34	In Stock	In Stock
2 mg	$48	In Stock	In Stock
5 mg	$80	In Stock	In Stock
10 mg	$128	In Stock	In Stock
25 mg	$288	In Stock	In Stock
50 mg	$433	In Stock	In Stock
100 mg	$579	In Stock	In Stock
200 mg	$826	-	In Stock
1 mL x 10 mM (in DMSO)	$128	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:>99.99%

Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).
Targets&IC50	PAR1:96 nM
In vitro	For analysis, platelet aggregometry was performed and the influence of epinephrine, adenosine diphosphate, collagen (Coll) and thrombin receptor-activated peptide (TRAP-6) as agonist were determined.?Compared to the control group, patients with venous thromboembolism showed an enhanced maximal platelet aggregation with low concentrations of TRAP-6 (2 microM) and collagen (0.05 microM)[1]
Synonyms	Thrombin Receptor Activator Peptide 6, PAR-1 agonist peptide

Chemical Properties

Molecular Weight	748.87
Formula	C₃₄H₅₆N₁₀O₉
Cas No.	141136-83-6
Smiles	CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O
Relative Density.	no data available
Sequence	Ser-Phe-Leu-Leu-Arg-Asn
Sequence Short	SFLLRN

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 33.33 mg/mL (44.51 mM), Sonication is recommended.

DMSO: 252.5 mg/mL (337.17 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3353 mL	6.6767 mL	13.3535 mL	66.7673 mL
5 mM	0.2671 mL	1.3353 mL	2.6707 mL	13.3535 mL
10 mM	0.1335 mL	0.6677 mL	1.3353 mL	6.6767 mL
20 mM	0.0668 mL	0.3338 mL	0.6677 mL	3.3384 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0267 mL	0.1335 mL	0.2671 mL	1.3353 mL
100 mM	0.0134 mL	0.0668 mL	0.1335 mL	0.6677 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc