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Anti-PIK3CA Antibody (8O55) (Synonyms: Phosphoinositide-3-kinase catalytic a polypeptide, Phosphatidylinositol ...)

Catalog No. TMAC-03285 Copy Product Info
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Anti-PIK3CA Antibody (8O55) is a Rabbit antibody targeting PIK3CA. Anti-PIK3CA Antibody (8O55) can be used in ICC/IF,IP,WB.

Anti-PIK3CA Antibody (8O55)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03285
Synonyms Phosphoinositide-3-kinase catalytic a polypeptide, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha, p110alpha)

Anti-PIK3CA Antibody (8O55) is a Rabbit antibody targeting PIK3CA. Anti-PIK3CA Antibody (8O55) can be used in ICC/IF,IP,WB.

Anti-PIK3CA Antibody
(8O55)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-PIK3CA Antibody (8O55) is a Rabbit antibody targeting PIK3CA. Anti-PIK3CA Antibody (8O55) can be used in ICC/IF,IP,WB.
SynonymsPhosphoinositide-3-kinase catalytic a polypeptide, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha, p110alpha)
Ig Type
IgG
Clone
8O55
Reactivity
Human,Mouse,Rat
Verified Activity
1. ICC staining PI 3 kinase p110 alpha in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
2. ICC staining PI 3 kinase p110 alpha in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining PI 3 kinase p110 alpha in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPhosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110δ expression is restricted to white blood cells. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ seems to have the capacity to autophosphorylate. p110γ does not interact with the p85 subunits. It has been shown to be activated by α and βγ heterotrimeric G proteins.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 124 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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