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Polyphyllin II (Synonyms: Chonglou Saponin II)

Catalog No. T3894 Copy Product Info
Purity: 99.92%
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Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.

Polyphyllin II

Copy Product Info
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Catalog No. T3894
Synonyms Chonglou Saponin II

Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.

Polyphyllin II
Cas No. 76296-72-5
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Pack SizePriceUSA StockGlobal StockQuantity
2 mg$32In Stock-
5 mg$50In Stock-
10 mg$85In Stock-
25 mg$139In Stock-
50 mg$198In Stock-
100 mg$297In Stock-
200 mg$459In Stock-
1 mL x 10 mM (in DMSO)$80In StockIn Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.92%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.
SynonymsChonglou Saponin II
Chemical Properties
Molecular Weight855.02
FormulaC44H70O16
Cas No.76296-72-5
Smiles[H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CC[C@@H](C)CO1)O2)O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@@H](CO)[C@H](O)[C@H]2O)C(O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H]1O
Relative Density.1.4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 250 mg/mL (292.39 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1696 mL5.8478 mL11.6956 mL58.4782 mL
5 mM0.2339 mL1.1696 mL2.3391 mL11.6956 mL
10 mM0.1170 mL0.5848 mL1.1696 mL5.8478 mL
20 mM0.0585 mL0.2924 mL0.5848 mL2.9239 mL
50 mM0.0234 mL0.1170 mL0.2339 mL1.1696 mL
100 mM0.0117 mL0.0585 mL0.1170 mL0.5848 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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