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Anti-STEAP3 Polyclonal Antibody is a Rabbit antibody targeting STEAP3. Anti-STEAP3 Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $528 | 7-10 days |
Description | Anti-STEAP3 Polyclonal Antibody is a Rabbit antibody targeting STEAP3. Anti-STEAP3 Polyclonal Antibody can be used in WB. |
Synonyms | Tumor suppressor-activated pathway protein 6, Tumor suppressor pHyde, Tumor suppressor activated pathway protein 6, TSAP6, TSAP 6, STMP3, STMP 3, STEAP3, STEAP family member 3 metalloreductase, STEAP family member 3, STEAP 3, STEA3, STEA 3, Six-transmembrane epithelial antigen of prostate 3, Six transmembrane prostate protein 3, Six transmembrane epithelial antigen of prostate 3, pHyde, MGC93147, Metalloreductase STEAP3, hTSAP6, hpHyde, Dudulin2, Dudulin 2, Dudlin2, Dudlin 2, 1010001D01Rik |
Ig Type | IgG |
Reactivity | Mouse (predicted:Human,Rat,Horse) |
Verified Activity | Sample: Liver (Mouse) Cell Lysate at 40 μg Primary: Anti-STEAP3 (TMAB-01789) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kDa Observed band size: 56 kDa |
Application | |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Endosome membrane. Localizes to vesicular-like structures at the plasma membrane and around the nucleus. |
Tissue Specificity | Expressed in adult bone marrow, placenta, liver, skeletal muscle and pancreas. Down-regulated in hepatocellular carcinoma. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Immunogen | KLH conjugated synthetic peptide: human STEAP3 |
Antigen Species | Human |
Gene Name | STEAP3 |
Gene ID | |
Protein Name | Metalloreductase STEAP3 |
Uniprot ID | |
Biology Area | Vitamins / minerals,Vitamins / Minerals |
Function | Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP. |
Molecular Weight | Theoretical: 56 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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