Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC HSP90 degrader BP3 potently and selectively degrades HSP90 through a CRBN-dependent mechanism. It effectively diminishes HSP90 protein levels in MCF-7 cells with a half-maximal degradation concentration (DC50) of 0.99 µM. Additionally, this compound impedes the proliferation of breast cancer cells [1].
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | PROTAC HSP90 degrader BP3 potently and selectively degrades HSP90 through a CRBN-dependent mechanism. It effectively diminishes HSP90 protein levels in MCF-7 cells with a half-maximal degradation concentration (DC50) of 0.99 µM. Additionally, this compound impedes the proliferation of breast cancer cells [1]. |
Molecular Weight | 641.08 |
Formula | C32H29ClN8O5 |
CAS No. | 2669072-88-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PROTAC HSP90 degrader BP3 2669072-88-0 PROTAC PROTACs inhibitor inhibit