B7-2/CD86 Protein, Rabbit, Recombinant (His)

Name: B7-2/CD86 Protein, Rabbit, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00959
Rating: 4.5 (1 reviews)

(Synonyms: T-lymphocyte activation antigen CD86, CD86, Activation B7-2 antigen) Copy Product Info

Synonyms: T-lymphocyte activation antigen CD86, CD86, Activation B7-2 antigen

Catalog No. TMPJ-00959 Copy Product Info

B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071.

B7-2/CD86 Protein, Rabbit, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$58	35 days	35 days
10 µg	$91	35 days	35 days
20 µg	$123	35 days	35 days
50 µg	$183	35 days	35 days
100 µg	$297	35 days	35 days
200 µg	$485	35 days	35 days
500 µg	$932	35 days	35 days
1 mg	$1,300	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071.
Species	Rabbit
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	P42071
Amino Acid	Ala23-Arg246
Construction	Ala23-Arg246
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	T-lymphocyte activation antigen CD86, CD86, Activation B7-2 antigen
Research Background	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.

Chemical Properties

Molecular Weight

38-70 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.