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Anti-KRT20 Antibody (9H184)
(Synonyms: type I cytoskeletal 20, Protein IT, KRT 20, Keratin-20, Keratin, K20, Cytokeratin-20, CK-20) Copy Product Info
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Synonyms: type I cytoskeletal 20, Protein IT, KRT 20, Keratin-20, Keratin, K20, Cytokeratin-20, CK-20
Catalog No. TMAB-01040 Copy Product Info
🥰Excellent
Anti-KRT20 Antibody (9H184) is a Rabbit antibody targeting KRT20. Anti-KRT20 Antibody (9H184) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-KRT20 Antibody
(9H184)
(9H184)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $153 | 7-10 days | 7-10 days | |
| 50 μL | $273 | 7-10 days | 7-10 days | |
| 100 μL | $488 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-KRT20 Antibody (9H184) is a Rabbit antibody targeting KRT20. Anti-KRT20 Antibody (9H184) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | type I cytoskeletal 20, Protein IT, KRT 20, Keratin-20, Keratin, K20, Cytokeratin-20, CK-20 |
| Ig Type | IgG |
| Clone | 9H184 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | FCM=1 μg/Test; ICC/IF=1:100-500; IF=1:200-1000; IHC-Fr=1:200-1000; IHC-P=1:200-1000; WB=1:1000-5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of t |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Cytokeratin 20 is a type I keratin which is primarily expressed in gastric and intestinal epithelium, urothelium, and Merkel-cells. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Their genes are clustered in a region of chromosome 17q12-q21. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. It is also expressed in adenocarcinomas of the colon, stomach, pancreas and the bile system and is present in mucinous ovarian tumors, transitional-cell and Merkel-cell carcinomas. Notably, the squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas lack cytokeratin 20. |
| Immunogen | A synthesized peptide: human Cytokeratin 20 |
| Antigen Species | Human |
| Gene Name | KRT20 |
| Gene ID | |
| Protein Name | Keratin, type I cytoskeletal 20 |
| Uniprot ID | |
| Biology Area | Tumor biomarkers,Cytokeratins |
| Function | Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). |
| Molecular Weight | Theoretical: 48 kDa. Actual: 45 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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