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pocapavir

Catalog No. T4492 CAS 146949-21-5

Synonyms: SCH-48973, V-073

Pocapavir (SCH-48973) is an investigational enterovirus (EV) capsid inhibitor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

pocapavir, CAS 146949-21-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 31.00
2 mg	In stock	$ 44.00
5 mg	In stock	$ 72.00
10 mg	In stock	$ 113.00
25 mg	In stock	$ 213.00
50 mg	In stock	$ 372.00
100 mg	In stock	$ 597.00
1 mL * 10 mM (in DMSO)	In stock	$ 79.00

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Purity: 98.21%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Pocapavir (SCH-48973) is an investigational enterovirus (EV) capsid inhibitor.

Synonyms	SCH-48973, V-073
Molecular Weight	423.72
Formula	C21H17Cl3O3
CAS No.	146949-21-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (118 mM)

H2O: Insoluble

References and Literature

1. Collett MS, et al. Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model. J Infect Dis. 2017 Feb 1;215(3):335-343. 2. Wittekind SG, et al. Neonatal Enterovirus Myocarditis With Severe Dystrophic Calcification: Novel Treatment WithPocapavir. J Investig Med High Impact Case Rep. 2017 Sep 14;5(3):2324709617729393.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Drug Repurposing Compound Library Bioactive Compound Library Nonsteroidal Anti-Inflammatory Compound Library ReFRAME Related Library NO PAINS Compound Library Immunology/Inflammation Compound Library Anti-Viral Compound Library Orally Active Compound Library Anti-Infection Compound Library

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Related compounds with same targets

Aspirin LabMol-319 Ibuzatrelvir (-)-Epicatechin gallate NGI-1 SARS-CoV-2 3CLpro-IN-15 STING agonist-1 Mavrilimumab

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below

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Step Two: Enter the in vivo formulation

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Reconstitution Calculation

Molecular Weight Calculator

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Molarity Calculator allows you to calculate the

Mass of a compound required to prepare a solution of known volume and concentration
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Concentration of a solution resulting from a known mass of compound in a specific volume

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

pocapavir 146949-21-5 Immunology/Inflammation Microbiology/Virology Virus Protease Antiviral polioendgame HEV SCH48973 Enterovirus HRVs polioviruses HRV SCH-48973 V 073 V073 Rhinovirus HEVs inhibit Inhibitor V-073 SCH 48973 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.