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Target / Pathway Focused

A target-focused library is a screening collection of compounds specifically tailored to modulate the function of a particular target or a protein family. These libraries not only reduce waste by eliminating compounds that are unlikely to bind to target proteins, but often lead to the increased potency and specificity of binders, as demonstrated for c-Src kinase. Compared to large and diverse screening libraries, using relatively small and targeted collections significantly improves the odds of finding potential drug candidates, thus further reduces the costs of drug discovery.

  • Protease Inhibitor Library
    L1100
    A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
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    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • DNA Damage & Repair Compound Library
    L3900
    A unique collection of 910 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
    • Inquiry Price
    Size
    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Kinase Inhibitor Library
    L1600
    A unique collection of 2720 kinase inhibitors regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;
    • Inquiry Price
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    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Cell Cycle Compound Library
    L8100
    A unique collection of 677 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
    • Inquiry Price
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    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • GPCR Compound Library
    L1500
    A unique collection of 1940 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;
    • Inquiry Price
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    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Neurotransmitter Receptor Compound Library
    L2610
    A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;
    • Inquiry Price
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    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Ion Channel Inhibitor Library
    L2300
    A unique collection of 1147 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
    • Inquiry Price
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    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Mitochondria-Targeted Compound Library
    L5300
    A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
    • Inquiry Price
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    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Epigenetics Compound Library
    L1200
    Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;
    • Inquiry Price
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    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Pyroptosis Compound Library
    L8720
    1066 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
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    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Neuronal Signaling Compound Library
    L2600
    A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;
    • Inquiry Price
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    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • MAPK Inhibitor Library
    L1400
    A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Nuclear Receptor Compound Library
    L1510
    A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;
    • Inquiry Price
    Size
    QTY
    TargetMol | Citations Cited
  • Tyrosine Kinase Inhibitor Library
    L2200
    A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;
    • Inquiry Price
    Size
    QTY
    TargetMol | Citations Cited
  • NF-κB Signaling Compound Library
    L3800
    A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Autophagy Compound Library
    L3200
    A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Wnt/Hedgehog/Notch Compound Library
    L4300
    A unique collection of 237 Wnt Hedgehog Notch signaling targeted compounds for high throughput and high content screening;
    • Inquiry Price
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    TargetMol | Citations Cited
  • TGF-beta/Smad Compound Library
    L4100
    A unique collection of 184 TGF-beta Smad signaling targeted compounds for high throughput and high content screening;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Potassium Channel Blocker Library
    L7300
    A unique collection of 152 potassium channel blockers and agonists for high throughput and high content screening;
    • Inquiry Price
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    QTY
    TargetMol | Citations Cited
  • AMPK-Targeted Compound Library
    L1120
    80 well-chosen unique AMPK-targeted small molecules;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Angiogenesis related Compound Library
    L4800
    A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
    • Inquiry Price
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    QTY
    TargetMol | Citations Cited
  • Chemokine Inhibitor Library
    L7600
    A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;
    • Inquiry Price
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    QTY
    TargetMol | Citations Cited
  • Adrenergic Receptor-Targeted Compound Library
    L2700
    A unique collection of 193 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;
    • Inquiry Price
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    TargetMol | Citations Cited
  • JAK-STAT Compound Library
    L3700
    A unique collection of 252 JAK STAT signaling targeted compounds for high throughput and high content screening;
    • Inquiry Price
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    TargetMol | Citations Cited
  • HIF-1 Signaling Pathway Compound Library
    L8500
    A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
    • Inquiry Price
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    QTY
    TargetMol | Citations Cited
  • Inhibitor Library
    L2000
    A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;
    • Inquiry Price
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    QTY
    TargetMol | Citations Cited
  • Phosphatase Inhibitor Library
    L9100
    A collection of 79 phosphatase inhibitors with known activity;
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    TargetMol | Citations Cited
  • GPCR Compound Library Plus
    L1580
    Well-chosen 338 GPCR targeting compounds with unique structures;
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    TargetMol | Citations Cited
  • Serotonin Receptor-Targeted Compound Library
    L2800
    A unique collection of 268 compounds targeting serotonin receptors for high throughput screening and high content screening;
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    TargetMol | Citations Cited
  • Methylation Compound Library
    L3510
    128 methylation-related compounds that can be used for high-throughput and high-content screening.
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    TargetMol | Citations Cited
  • PI3K-AKT-mTOR Compound Library
    L1300
    A unique collection of 420 compounds targeting PI3K Akt mTOR signaling for research in PI3K Akt mTOR signaling, and drug discovery in diseases involved with PI3K Akt mTOR signaling;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Ferroptosis Compound Library
    L8700
    A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study;
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    TargetMol | Citations Cited
  • Microtubule-Targeted Compound Library
    L1110
    A unique collection of 142 microtubule-targeted compounds can be used in HTS and HCS;
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    TargetMol | Citations Cited
  • Cytokine Inhibitor Library
    L3600
    A unique collection of 604 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Endoplasmic Reticulum Stress Compound Library
    L9700
    A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
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    TargetMol | Citations Cited
  • Apoptosis Compound Library
    L9000
    A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Cytoskeletal Signaling Pathway Compound Library
    L1310
    A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Sodium Channel Blocker Library
    L7400
    A unique collection of 118 sodium channel blockers and agonists for high throughput and high content screening;
    • Inquiry Price
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    QTY
    TargetMol | Citations Cited
  • Calcium Channel Compound Library
    L7200
    A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;
    • Inquiry Price
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    QTY
    TargetMol | Citations Cited
  • FDA-Approved Kinase Inhibitor Library
    L1610
    A unique collection of 263 kinase inhibitors regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
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    TargetMol | Citations Cited
  • Histamine & Melatonin Receptor-Targeted Compound Library
    L3300
    A unique collection of 153 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;
    • Inquiry Price
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    TargetMol | Citations Cited
  • Ubiquitination Compound Library
    L8600
    A unique collection of 210 ubiquitination related small chemicals can be used for high throughput and high content screening;
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    TargetMol | Citations Cited
  • Cuproptosis Compound Library
    L8710
    TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.
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    TargetMol | Citations Cited
  • Exosome Compound Library
    L9420
    76 exosome-related compounds that can be used for high-throughput and high-content screening.
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    TargetMol | Citations Cited