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KOdiA-PC

Name: KOdiA-PC
Brand: TargetMol
SKU: T36172
Rating: 4.5 (1 reviews)

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Catalog No. T36172Cas No. 439904-33-3

KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.

KOdiA-PC

😃Good

Catalog No. T36172Cas No. 439904-33-3

KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.

Pack Size	Price	USA Warehouse	Global Warehouse
500 μg	$198	35 days	35 days
1 mg	$388	35 days	35 days
5 mg	$1,430	35 days	35 days
10 mg	$2,560	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.
In vitro	KOdiA-PC inhibited LPS-induced macrophage migration. [1]
In vivo	In a mouse model of acute lung injury induced by intranasal injection of HKSA, intravenous injection of KOdiA-PC(10 mg/kg) increased HKSA-induced BAL protein content and cell count, as well as tissue expression of TNF-α, KC, IL1β and CCL2. And promoted blood vessel leakage in Evans Blue's lung infiltration monitoring. [2]

Chemical Properties

Molecular Weight	663.78
Formula	C₃₂H₅₈NO₁₁P
Cas No.	439904-33-3
Smiles	[C@H](OC(CCCC(/C=C/C(O)=O)=O)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCC)=O

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

PBS (pH7.2): 5 mg/mL (7.53 mM), Sonication is recommended.

DMSO: < 1 mg/mL (insoluble or slightly soluble)

PBS (pH 7.2): 1.00 mg/mL (1.51 mM), Sonication is recommended.

Ethanol: 10.00 mg/mL (15.07 mM), Sonication is recommended.

DMF: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

PBS (pH7.2)/Ethanol

	1mg	5mg	10mg	50mg
5 mM	0.3013 mL	1.5065 mL	3.0130 mL	15.0652 mL

Ethanol

	1mg	5mg	10mg	50mg
10 mM	0.1507 mL	0.7533 mL	1.5065 mL	7.5326 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc