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Fluphenazine-N-2-chloroethane (hydrochloride)

(Synonyms: SKF-7171A hydrochloride) Copy Product Info
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Synonyms: SKF-7171A hydrochloride

Catalog No. T36820 Copy Product Info
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Fluphenazine-N-2-chloroethane hydrochloride is a fluphenazine derivative containing a chloroethyl alkyl group that forms covalent bonds with calmodulin; it is commonly used as a chemical probe for studying calmodulin function and related signaling pathways.
Fluphenazine-N-2-chloroethane (hydrochloride)
Cas No. 3892-78-2
Pack SizePriceUSA StockGlobal StockQuantity
10 mg$11335 days35 days
25 mg$22935 days35 days
50 mg$36235 days35 days
100 mg$66735 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
Fluphenazine-N-2-chloroethane hydrochloride is a fluphenazine derivative containing a chloroethyl alkyl group that forms covalent bonds with calmodulin; it is commonly used as a chemical probe for studying calmodulin function and related signaling pathways.
In vitro
Fluphenazine-N-2-chloroethane hydrochloride hydrochloride (10 µM) reduces the production of NO induced by 0.1 mM CORM-2 in alveolar cells [2].
SynonymsSKF-7171A hydrochloride
Chemical Properties
Molecular Weight528.89
FormulaC22H27Cl3F3N3S
Cas No.3892-78-2
SmilesFC(F)(C1=CC=C2SC3=C(N(CCCN4CCN(CC4)CCCl)C2=C1)C=CC=C3)F.Cl.Cl
Relative Density.1.274g/cm3
Storage & Solubility Information
StorageKeep away from moistureKeep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 8 mg/mL (15.13 mM), Sonication is recommended.
DMF: 10 mg/mL (18.91 mM), Sonication is recommended.
Ethanol: 1 mg/mL (1.89 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO/DMF
1mg5mg10mg50mg
1 mM1.8908 mL9.4538 mL18.9075 mL94.5376 mL
DMSO/DMF
1mg5mg10mg50mg
5 mM0.3782 mL1.8908 mL3.7815 mL18.9075 mL
10 mM0.1891 mL0.9454 mL1.8908 mL9.4538 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Keywords

Related Tags: Fluphenazine-N-2-chloroethane (hydrochloride) chemical structure | Fluphenazine-N-2-chloroethane (hydrochloride) in vitro | Fluphenazine-N-2-chloroethane (hydrochloride) formula | Fluphenazine-N-2-chloroethane (hydrochloride) molecular weight