Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and PARP15, with IC50 values of 27 μM and 11 μM, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 98.00 | |
25 mg | In stock | $ 185.00 | |
50 mg | In stock | $ 328.00 | |
100 mg | In stock | $ 538.00 | |
500 mg | In stock | $ 1,150.00 |
Description | PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and PARP15, with IC50 values of 27 μM and 11 μM, respectively. |
Targets&IC50 | PARP10 (human):3.64 μM, PARP15 (human):11 μM, PARP2 (human):27 μM |
In vitro | PARP10-IN-2 (Compound 10) has an IC50 of 1-2 μM by clonogenic assay (CFA) in HeLa-PARP10 cells.[1] |
Molecular Weight | 238.24 |
Formula | C14H10N2O2 |
CAS No. | 1042780-52-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225.0 mg/mL (944.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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PARP10-IN-2 1042780-52-8 Chromatin/Epigenetic DNA Damage/DNA Repair PARP inhibitor inhibit