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N-(3-Aminopropyl)cyclohexylamine

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Catalog No. T35878Cas No. 3312-60-5

N-(3-Aminopropyl)cyclohexylamine, a derivative of cyclohexylamine, acts as a selective and competitive inhibitor of spermine synthase, making it suitable for research on neurological diseases [1].

N-(3-Aminopropyl)cyclohexylamine

N-(3-Aminopropyl)cyclohexylamine

🥰Excellent
Purity: 98.82%
Catalog No. T35878Cas No. 3312-60-5
N-(3-Aminopropyl)cyclohexylamine, a derivative of cyclohexylamine, acts as a selective and competitive inhibitor of spermine synthase, making it suitable for research on neurological diseases [1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$42In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.82%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
N-(3-Aminopropyl)cyclohexylamine, a derivative of cyclohexylamine, acts as a selective and competitive inhibitor of spermine synthase, making it suitable for research on neurological diseases [1].
In vitro
N-(3-Aminopropyl)cyclohexylamine at concentrations up to 10(-6) M did not affect the neuronal survival, but significantly blocked the survival-promoting effect of spermine (10(-8) M) [1]. APCHA also blocked the spermine-induced promotion of neurite regeneration following axotomy [1]. In primary cultured brain neurons, APCHA works as a spermine antagonist rather than as a spermine synthesis inhibitor [1].
Chemical Properties
Molecular Weight156.2685
FormulaC9H20N2
Cas No.3312-60-5
SmilesNCCCNC1CCCCC1
Relative Density.0.917 g/cm3 at 25℃ (lit.)
Storage & Solubility Information
Storagekeep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 95 mg/mL (607.93 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM6.3992 mL31.9962 mL63.9924 mL319.9621 mL
5 mM1.2798 mL6.3992 mL12.7985 mL63.9924 mL
10 mM0.6399 mL3.1996 mL6.3992 mL31.9962 mL
20 mM0.3200 mL1.5998 mL3.1996 mL15.9981 mL
50 mM0.1280 mL0.6399 mL1.2798 mL6.3992 mL
100 mM0.0640 mL0.3200 mL0.6399 mL3.1996 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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