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Anti-KRT18 Polyclonal Antibody
(Synonyms: type I cytoskeletal 18, KRT18, Keratin-18 (K18), Keratin, type I cytoskeletal 18, Cytokeratin-18 (CK-18), CYK18, Cell proliferation-inducing gene 46 protein) Copy Product Info
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Synonyms: type I cytoskeletal 18, KRT18, Keratin-18 (K18), Keratin, type I cytoskeletal 18, Cytokeratin-18 (CK-18), CYK18, Cell proliferation-inducing gene 46 protein
Catalog No. TMAB-01036 Copy Product Info
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Anti-KRT18 Polyclonal Antibody is a Rabbit antibody targeting KRT18. Anti-KRT18 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-KRT18 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-KRT18 Polyclonal Antibody is a Rabbit antibody targeting KRT18. Anti-KRT18 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | type I cytoskeletal 18, KRT18, Keratin-18 (K18), Keratin, type I cytoskeletal 18, Cytokeratin-18 (CK-18), CYK18, Cell proliferation-inducing gene 46 protein |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Rabbit) |
| Application | |
| Recommended Dose | FCM=0.2 μg/Test; ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, perinuclear region. Nucleus, nucleolus. |
| Tissue Specificity | Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human CK18 |
| Antigen Species | Human |
| Gene Name | KRT18 |
| Gene ID | |
| Protein Name | Keratin, type I cytoskeletal 18 |
| Uniprot ID | |
| Biology Area | Cytokeratins,Tumor Associated |
| Function | When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. |
| Molecular Weight | Theoretical: 48 kDa. Actual: 48 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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