The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 487.00 | |
500 μg | 5 days | $ 1,950.00 | |
1 mg | 5 days | $ 3,250.00 |
Description | The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. |
Species | Cynomolgus |
Expression System | HEK293 |
Tag | C-His |
Accession Number | G7PHZ7 |
Synonyms | TIFIL-23, IL-22, IL-D110, IL-TIF, TIFa, Interleukin-22, Cytokine Zcyto18, ZCYTO18 |
Construction | Recombinant Cynomolgus IL-22 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ala34-Ile179.[Accession |G7PHZ7] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 17.69 kDa. Due to glycosylation, the protein migrates to 32-42 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. |
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Please read the User Guide of Recombinant Proteins for more specific information.
IL-22 Protein, Cynomolgus, Recombinant (His) ZCYTO-18 TIFIL-23 TIFIL23 IL-22 IL-D110 IL-TIF IL-D 110 IL 22 ZCYTO 18 TIFa IL22 Interleukin-22 IL-D-110 Cytokine Zcyto18 TIFIL 23 ZCYTO18 recombinant recombinant-proteins proteins protein