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Calpain-2-IN-1

🥰Excellent
Catalog No. T63708Cas No. 144231-85-6

Calpain-2-IN-1 (Formula 1A) is a selective calpain-2 inhibitor with Ki values of 181 nM for calpain-1 and 7.8 nM for calpain-2, applicable for neurodegenerative diseases and other synaptic dysfunction disorders.

Calpain-2-IN-1

Calpain-2-IN-1

🥰Excellent
Catalog No. T63708Cas No. 144231-85-6
Calpain-2-IN-1 (Formula 1A) is a selective calpain-2 inhibitor with Ki values of 181 nM for calpain-1 and 7.8 nM for calpain-2, applicable for neurodegenerative diseases and other synaptic dysfunction disorders.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$249-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Calpain-2-IN-1 (Formula 1A) is a selective calpain-2 inhibitor with Ki values of 181 nM for calpain-1 and 7.8 nM for calpain-2, applicable for neurodegenerative diseases and other synaptic dysfunction disorders.
Chemical Properties
Molecular Weight527.61
FormulaC28H37N3O7
Cas No.144231-85-6
SmilesC(NC(C([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(C)C)=O)CC)=O)=O)C2=CC(OC)=CC(OC)=C2
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (151.63 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8953 mL9.4767 mL18.9534 mL94.7670 mL
5 mM0.3791 mL1.8953 mL3.7907 mL18.9534 mL
10 mM0.1895 mL0.9477 mL1.8953 mL9.4767 mL
20 mM0.0948 mL0.4738 mL0.9477 mL4.7383 mL
50 mM0.0379 mL0.1895 mL0.3791 mL1.8953 mL
100 mM0.0190 mL0.0948 mL0.1895 mL0.9477 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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