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Anti-PSIP1 Antibody (7I174) (Synonyms: Transcriptional coactivator p75/p52, PSIP2, PSIP1, PC4 and SFRS1-inter...)

Catalog No. TMAC-03452 Copy Product Info
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Anti-PSIP1 Antibody (7I174) is a Mouse antibody targeting PSIP1. Anti-PSIP1 Antibody (7I174) can be used in ICC,IHC,WB.

Anti-PSIP1 Antibody (7I174)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03452
Synonyms Transcriptional coactivator p75/p52, PSIP2, PSIP1, PC4 and SFRS1-interacting protein, Lens epithelium-derived growth factor, LEDGF, DFS70, Dense fine speckles 70 kDa protein (DFS 70), CLL-associated antigen KW-7

Anti-PSIP1 Antibody (7I174) is a Mouse antibody targeting PSIP1. Anti-PSIP1 Antibody (7I174) can be used in ICC,IHC,WB.

Anti-PSIP1 Antibody
(7I174)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PSIP1 Antibody (7I174) is a Mouse antibody targeting PSIP1. Anti-PSIP1 Antibody (7I174) can be used in ICC,IHC,WB.
SynonymsTranscriptional coactivator p75/p52, PSIP2, PSIP1, PC4 and SFRS1-interacting protein, Lens epithelium-derived growth factor, LEDGF, DFS70, Dense fine speckles 70 kDa protein (DFS 70), CLL-associated antigen KW-7
Clone
7I174
Reactivity
Human,Monkey,Rat
Verified Activity
1. Western blot analysis of PSIP1 on different cell lysates using anti-PSIP1 antibody at 1/1,000 dilution. Positive control: Lane 1: HepG2, Lane 2: Jurkat, Lane 3: K562, Lane 4: Cos7, Lane 5: PC-12, Lane 6: Hela, Lane 7: NIH/3T3.
2. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-PSIP1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded brain tissue using anti-PSIP1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-PSIP1 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-PSIP1 antibody. Counter stained with hematoxylin.
6. ICC staining PSIP1 (green) and actin filaments (red) in NIH/3T3 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:100-500; ICC: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
Research BackgroundPSIP1 (PC4 and SFRS1 interacting protein 1), also known as CLL-associated antigen KW-7, PSIP2, LEDGF (lens epithelium-derived growth factor), PAIP, DFS70 (dense fine speckles 70 kDa protein) or transcriptional coactivator p75/p52, is a 530 amino acid nuclear protein that associates with chromatin throughout the cell cycle. Functioning as a transcriptional coactivator that complexes with the human immunodeficiency virus type 1 (HIV-1) integrase, PSIP1 is essential for the nuclear localization and chromosomal association of viral proteins. As the primary integrase-to-chromatin tethering factor for HIV-1, PSIP1 is responsible for the cellular trafficking of lentiviral integrases. During apoptosis, PSIP1 is cleaved at three sites by caspase-3 and caspase-7, contributing to the pathogenesis of atopic disorders.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 75 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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