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Anti-PSIP1 Antibody (7I174)
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Catalog No. TMAC-03452
Alias Transcriptional coactivator p75/p52, PSIP2, PSIP1, PC4 and SFRS1-interacting protein, Lens epithelium-derived growth factor, LEDGF, DFS70, Dense fine speckles 70 kDa protein (DFS 70), CLL-associated antigen KW-7
Anti-PSIP1 Antibody (7I174) is a Mouse antibody targeting PSIP1. Anti-PSIP1 Antibody (7I174) can be used in WB,ICC,IHC.
Anti-PSIP1 Antibody (7I174)
Anti-PSIP1 Antibody (7I174)
😃Good
Catalog No. TMAC-03452Alias Transcriptional coactivator p75/p52, PSIP2, PSIP1, PC4 and SFRS1-interacting protein, Lens epithelium-derived growth factor, LEDGF, DFS70, Dense fine speckles 70 kDa protein (DFS 70), CLL-associated antigen KW-7
Anti-PSIP1 Antibody (7I174) is a Mouse antibody targeting PSIP1. Anti-PSIP1 Antibody (7I174) can be used in WB,ICC,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $427 | 7-10 days |
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Chemical Properties
| Description | Anti-PSIP1 Antibody (7I174) is a Mouse antibody targeting PSIP1. Anti-PSIP1 Antibody (7I174) can be used in WB,ICC,IHC. |
| Synonyms | Transcriptional coactivator p75/p52, PSIP2, PSIP1, PC4 and SFRS1-interacting protein, Lens epithelium-derived growth factor, LEDGF, DFS70, Dense fine speckles 70 kDa protein (DFS 70), CLL-associated antigen KW-7 |
| Clone | 7I174 |
| Reactivity | Human,Monkey,Rat |
| Verified Activity | 1. Western blot analysis of PSIP1 on different cell lysates using anti-PSIP1 antibody at 1/1,000 dilution. Positive control: Lane 1: HepG2, Lane 2: Jurkat, Lane 3: K562, Lane 4: Cos7, Lane 5: PC-12, Lane 6: Hela, Lane 7: NIH/3T3. 2. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-PSIP1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded brain tissue using anti-PSIP1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-PSIP1 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-PSIP1 antibody. Counter stained with hematoxylin. 6. ICC staining PSIP1 (green) and actin filaments (red) in NIH/3T3 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:100-500; ICC: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Research Background | PSIP1 (PC4 and SFRS1 interacting protein 1), also known as CLL-associated antigen KW-7, PSIP2, LEDGF (lens epithelium-derived growth factor), PAIP, DFS70 (dense fine speckles 70 kDa protein) or transcriptional coactivator p75/p52, is a 530 amino acid nuclear protein that associates with chromatin throughout the cell cycle. Functioning as a transcriptional coactivator that complexes with the human immunodeficiency virus type 1 (HIV-1) integrase, PSIP1 is essential for the nuclear localization and chromosomal association of viral proteins. As the primary integrase-to-chromatin tethering factor for HIV-1, PSIP1 is responsible for the cellular trafficking of lentiviral integrases. During apoptosis, PSIP1 is cleaved at three sites by caspase-3 and caspase-7, contributing to the pathogenesis of atopic disorders. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 75 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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