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Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKDC (Thr2609). Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $318 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKDC (Thr2609). Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody can be used in WB. |
| Synonyms | XRCC7, XRCC 7, Protein Kinase DNA Activated Catalytic Polypeptide, PRKDC (p-Thr2609), PRKDC (p-T2609), PRKDC, p-PRKDC (Thr2609), p-PRKDC (T2609), PKRDC, Phospho-PRKDC (T2609), p460, p350, IMD26, HYRC1, HYRC 1, HYRC, Hyperradiosensitivity complementing 1, Hyper radiosensitivity of murine scid mutation, DNPK1, DNPK 1, DNA-PKcs, DNAPK catalytic subunit, DNAPK, DNA PK catalytic subunit, DNA dependent protein kinase catalytic subunit, complementing 1 |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of extracts from K562 cells untreated (lane 1) or treated with hydroxyurea (lane 2) using DNA PKcs (Phospho-Thr2609) antibody TMAC-01157. ![]() |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 2609 (V-E-T(p)-Q-A) derived from Human DNA-PK |
| Antigen Species | human |
| Uniprot ID |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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