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Desmethylene Paroxetine hydrochloride

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Catalog No. T37308Cas No. 1394861-12-1

Desmethylene Paroxetine hydrochloride is a non-conjugated metabolite of Paroxetine, a catechol intermediate.

Desmethylene Paroxetine hydrochloride

Desmethylene Paroxetine hydrochloride

😃Good
Catalog No. T37308Cas No. 1394861-12-1
Desmethylene Paroxetine hydrochloride is a non-conjugated metabolite of Paroxetine, a catechol intermediate.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$15535 days35 days
10 mg$28835 days35 days
50 mg$82535 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
Desmethylene Paroxetine hydrochloride is a non-conjugated metabolite of Paroxetine, a catechol intermediate.
Chemical Properties
Molecular Weight353.82
FormulaC18H21ClFNO3
Cas No.1394861-12-1
SmilesC(OC1=CC(O)=C(O)C=C1)[C@H]2[C@@H](CCNC2)C3=CC=C(F)C=C3.Cl
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 10 mg/mL (28.26 mM), Sonication is recommended.
H2O: 8 mg/mL (22.61 mM), Sonication is recommended.
Ethanol: 20 mg/mL (56.53 mM), Sonication is recommended.
DMSO: 8 mg/mL (22.61 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO/DMF/Ethanol
1mg5mg10mg50mg
1 mM2.8263 mL14.1315 mL28.2630 mL141.3148 mL
5 mM0.5653 mL2.8263 mL5.6526 mL28.2630 mL
10 mM0.2826 mL1.4131 mL2.8263 mL14.1315 mL
20 mM0.1413 mL0.7066 mL1.4131 mL7.0657 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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