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1-(7-carbamimidamidoheptyl)guanidine 2HCl

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Catalog No. T50092Cas No. 2193061-39-9
Alias 1,1'-(Heptane-1,7-diyl)diguanidine 2HCl, 1-(7-carbamimidamidoheptyl)guanidine dihydrochloride

1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerative diseases.

1-(7-carbamimidamidoheptyl)guanidine 2HCl

1-(7-carbamimidamidoheptyl)guanidine 2HCl

😃Good
Catalog No. T50092Alias 1,1'-(Heptane-1,7-diyl)diguanidine 2HCl, 1-(7-carbamimidamidoheptyl)guanidine dihydrochlorideCas No. 2193061-39-9
1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerative diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$86InquiryInquiry
5 mg$198InquiryInquiry
10 mg$298InquiryInquiry
25 mg$475InquiryInquiry
50 mg$672InquiryInquiry
100 mg$912InquiryInquiry
200 mg$1,190InquiryInquiry
1 mL x 10 mM (in DMSO)$190InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerative diseases.
Synonyms1,1'-(Heptane-1,7-diyl)diguanidine 2HCl, 1-(7-carbamimidamidoheptyl)guanidine dihydrochloride
Chemical Properties
Molecular Weight287.23
FormulaC9H24Cl2N6
Cas No.2193061-39-9
SmilesNC(NCCCCCCCNC(N)=N)=N.[H]Cl.[H]Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (174.08 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4815 mL17.4077 mL34.8153 mL174.0765 mL
5 mM0.6963 mL3.4815 mL6.9631 mL34.8153 mL
10 mM0.3482 mL1.7408 mL3.4815 mL17.4077 mL
20 mM0.1741 mL0.8704 mL1.7408 mL8.7038 mL
50 mM0.0696 mL0.3482 mL0.6963 mL3.4815 mL
100 mM0.0348 mL0.1741 mL0.3482 mL1.7408 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

1,1'(Heptane1,7diyl)diguanidine dihydrochloride1,1'-(Heptane-1,7-diyl)diguanidine1,1' (Heptane 1,7 diyl)diguanidine dihydrochloride1-(7-carbamimidamidoheptyl)guanidine
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