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1-(7-carbamimidamidoheptyl)guanidine 2HCl (Synonyms: 1,1'-(Heptane-1,7-diyl)diguanidine 2HCl, 1-(7-carbamimidam...)

Name: 1-(7-carbamimidamidoheptyl)guanidine 2HCl
Brand: TargetMol
SKU: T50092
Rating: 4.5 (1 reviews)

Catalog No. T50092 Copy Product Info

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1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerative diseases.

1-(7-carbamimidamidoheptyl)guanidine 2HCl

Copy Product Info

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Catalog No. T50092

Synonyms 1,1'-(Heptane-1,7-diyl)diguanidine 2HCl, 1-(7-carbamimidamidoheptyl)guanidine dihydrochloride

1-(7-carbamimidamidoheptyl)guanidine 2HCl

Cas No. 2193061-39-9

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Pack Size	Price	USA Stock	Global Stock
1 mg	$86	Inquiry	Inquiry
5 mg	$198	Inquiry	Inquiry
10 mg	$298	Inquiry	Inquiry
25 mg	$475	Inquiry	Inquiry
50 mg	$672	Inquiry	Inquiry
100 mg	$912	Inquiry	Inquiry
200 mg	$1,190	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$190	Inquiry	Inquiry

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerative diseases.
Synonyms	1,1'-(Heptane-1,7-diyl)diguanidine 2HCl, 1-(7-carbamimidamidoheptyl)guanidine dihydrochloride

Chemical Properties

Molecular Weight	287.23
Formula	C₉H₂₄Cl₂N₆
Cas No.	2193061-39-9
Smiles	NC(NCCCCCCCNC(N)=N)=N.[H]Cl.[H]Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (174.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4815 mL	17.4077 mL	34.8153 mL	174.0765 mL
5 mM	0.6963 mL	3.4815 mL	6.9631 mL	34.8153 mL
10 mM	0.3482 mL	1.7408 mL	3.4815 mL	17.4077 mL
20 mM	0.1741 mL	0.8704 mL	1.7408 mL	8.7038 mL
50 mM	0.0696 mL	0.3482 mL	0.6963 mL	3.4815 mL
100 mM	0.0348 mL	0.1741 mL	0.3482 mL	1.7408 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

1,1'(Heptane1,7diyl)diguanidine dihydrochloride1,1'-(Heptane-1,7-diyl)diguanidine1,1' (Heptane 1,7 diyl)diguanidine dihydrochloride1-(7-carbamimidamidoheptyl)guanidine

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