CD47 Protein, Human, Recombinant (mFc)

Name: CD47 Protein, Human, Recombinant (mFc)
Brand: TargetMol
SKU: TMPJ-00212
Rating: 4.5 (1 reviews)

(Synonyms: Protein MER6, MER6, Leukocyte surface antigen CD47, Integrin-associated protein, IAP, CD47, Antigenic surface determinant protein OA3) Copy Product Info

Synonyms: Protein MER6, MER6, Leukocyte surface antigen CD47, Integrin-associated protein, IAP, CD47, Antigenic surface determinant protein OA3

Catalog No. TMPJ-00212 Copy Product Info

CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 48-65 KDa and the accession number is Q08722.

Pack Size	Price	USA Stock	Global Stock
5 µg	$54	7-10 days	7-10 days
10 µg	$85	7-10 days	7-10 days
20 µg	$127	7-10 days	7-10 days
50 µg	$222	7-10 days	7-10 days
100 µg	$397	7-10 days	7-10 days
200 µg	$715	7-10 days	7-10 days
500 µg	$1,570	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Loaded Anti-Human CD47 mAb-Fc on AHC Biosensor, can bind Human CD47-mFc with an affinity constant of 0.08 nM as determined in BLI assay. (Regularly tested)
Description	CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 48-65 KDa and the accession number is Q08722.
Species	Human
Expression System	HEK293 Cells
Tag	C-mFc
Accession Number	Q08722
Amino Acid	Gln19-Pro139
Construction	Gln19-Pro139
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Protein MER6, MER6, Leukocyte surface antigen CD47, Integrin-associated protein, IAP, CD47, Antigenic surface determinant protein OA3
Research Background	CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

Chemical Properties

Molecular Weight

48-65 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.