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Anti-PSENEN Antibody (3P624)

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Catalog No. TMAC-03154

Anti-PSENEN Antibody (3P624) is a Rabbit antibody targeting PSENEN. Anti-PSENEN Antibody (3P624) can be used in WB,ICC,IHC,FCM.

Anti-PSENEN Antibody (3P624)

Anti-PSENEN Antibody (3P624)

😃Good
Catalog No. TMAC-03154
Anti-PSENEN Antibody (3P624) is a Rabbit antibody targeting PSENEN. Anti-PSENEN Antibody (3P624) can be used in WB,ICC,IHC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-PSENEN Antibody (3P624) is a Rabbit antibody targeting PSENEN. Anti-PSENEN Antibody (3P624) can be used in WB,ICC,IHC,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundFour proteins comprise the gamma-secretase complex: presenilin, nicastrin, aph-1, and PEN-2. Together, these proteins mediate cell surface signaling pathways for a variety of type I membrane proteins, notably amyloid-beta precursor protein, a protein implicated in the development of Alzheimer's disease, via intramembrane proteolysis. The proteins assemble into a proteolytically active complex in the golgi/trans-golgi network (TGN) compartments. Assembly leads to autocleavage of presenilin into two subunits to create the active site of gamma-secretase, an important step in understanding the mechanisms involved in the etiology and possible treatment of Alzheimer's disease.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized peptide: C-terminal human PEN2
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 12 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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