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Anti-PSENEN Antibody (3P624)

(Synonyms: PSENEN, Presenilin enhancer protein 2, PEN2, Gamma-secretase subunit PEN-2) Copy Product Info
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Synonyms: PSENEN, Presenilin enhancer protein 2, PEN2, Gamma-secretase subunit PEN-2

Catalog No. TMAC-03154 Copy Product Info
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Anti-PSENEN Antibody (3P624) is a Rabbit antibody targeting PSENEN. Anti-PSENEN Antibody (3P624) can be used in FCM,ICC,IHC,WB.
Anti-PSENEN Antibody
(3P624)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PSENEN Antibody (3P624) is a Rabbit antibody targeting PSENEN. Anti-PSENEN Antibody (3P624) can be used in FCM,ICC,IHC,WB.
SynonymsPSENEN, Presenilin enhancer protein 2, PEN2, Gamma-secretase subunit PEN-2
Ig Type
IgG
Clone
3P624
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundFour proteins comprise the gamma-secretase complex: presenilin, nicastrin, aph-1, and PEN-2. Together, these proteins mediate cell surface signaling pathways for a variety of type I membrane proteins, notably amyloid-beta precursor protein, a protein implicated in the development of Alzheimer's disease, via intramembrane proteolysis. The proteins assemble into a proteolytically active complex in the golgi/trans-golgi network (TGN) compartments. Assembly leads to autocleavage of presenilin into two subunits to create the active site of gamma-secretase, an important step in understanding the mechanisms involved in the etiology and possible treatment of Alzheimer's disease.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized peptide: C-terminal human PEN2
Antigen Species
Human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 12 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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