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Anti-CCL20 Antibody (2P759)

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Catalog No. TMAY-00889

Anti-CCL20 Antibody (2P759) is a Mouse antibody targeting CCL20. Anti-CCL20 Antibody (2P759) can be used in ELISA,ELISA(Det).

Anti-CCL20 Antibody (2P759)

Anti-CCL20 Antibody (2P759)

😃Good
Catalog No. TMAY-00889
Anti-CCL20 Antibody (2P759) is a Mouse antibody targeting CCL20. Anti-CCL20 Antibody (2P759) can be used in ELISA,ELISA(Det).
Pack SizePriceAvailabilityQuantity
20 μL$69 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CCL20 Antibody (2P759) is a Mouse antibody targeting CCL20. Anti-CCL20 Antibody (2P759) can be used in ELISA,ELISA(Det).
Ig Type
Monoclonal Mouse IgG1
Clone
2P759
Reactivity
Human
Application
ELISA,ELISA(Det)
Recommended Dose
ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CCL20 / MIP-3 alpha / MIP3A (rh CCL20 / MIP-3 alpha / MIP3A; TMPY-03935; P78556-1; Ala27-Met96). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundChemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products (including LPS, dsRNA, and PMA). MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CCL20 / MIP-3 alpha / MIP3A Protein (TMPY-03935)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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