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HGF Protein, Human, Recombinant (hFc)

(Synonyms: SF, HPTA, HGFB, HGF, Hepatopoietin-A, F-TCFB, F-TCF, DFNB39) Copy Product Info

Synonyms: SF, HPTA, HGFB, HGF, Hepatopoietin-A, F-TCFB, F-TCF, DFNB39

Catalog No. TMPK-00369 Copy Product Info
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in β-cell homeostasis; and is capable of modulating the inflammatory response.HGF plays a central role in these metabolic disorders,HGF levels could be employed as a biomarker for disease status/progression, and HGF/c-Met signaling pathway modulators could effectively regulate IR and treat diabetes.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$637-10 days7-10 days
10 μg$100-In Stock
20 μg$1637-10 days7-10 days
50 μg$3187-10 days7-10 days
100 μg$533In StockIn Stock
200 μg$9697-10 days7-10 days
500 μg$2,1307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95%
Appearance:Solution
Color:Transparent
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Product Introduction

Bioactivity
Bioactivity
HGF Protein, Human, Recombinant (hFc)
Description
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in β-cell homeostasis; and is capable of modulating the inflammatory response.HGF plays a central role in these metabolic disorders,HGF levels could be employed as a biomarker for disease status/progression, and HGF/c-Met signaling pathway modulators could effectively regulate IR and treat diabetes.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP14210-1
ConstructionGln32-Ser728
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
HGF Protein, Human, Recombinant (hFc)HGF Protein, Human, Recombinant (hFc)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 100 mM L-arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsSF, HPTA, HGFB, HGF, Hepatopoietin-A, F-TCFB, F-TCF, DFNB39
Research Background
Chemical Properties
Molecular WeightThe HGF single chain can be processed into the active form of disulfide-linked heterodimer of α and β chain.The protein has a predicted MW of 79.6 kDa (after cleavage of the signal peptide). Due to glycosylation, the protein migrates to 60-65 kDa correspo.
Storage & Solubility Information
StorageStore at -80°C Shipping with blue ice/Shipping at ambient temperature.

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Keywords

Related Tags: HGF Protein, Human, Recombinant (hFc) chemical structure | HGF Protein, Human, Recombinant (hFc) molecular weight