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Anti-NCX3 Polyclonal Antibody is a Rabbit antibody targeting NCX3. Anti-NCX3 Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $527 | 7-10 days |
Description | Anti-NCX3 Polyclonal Antibody is a Rabbit antibody targeting NCX3. Anti-NCX3 Polyclonal Antibody can be used in WB. |
Synonyms | Solute carrier family 8 sodium calcium exchanger member 3, Sodium/calcium exchanger SLC8A3, Sodium/calcium exchanger 3, Sodium calcium exchanger form 3, SCL8A3, NCX3, NAC3, Na+/Ca2+exchanger 3, Na+/Ca2+exchange protein 3, Na(+)/Ca(2+)-exchange protein 3, MGC90626, AW742262 |
Ig Type | IgG |
Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
Verified Activity | Sample: Lane 1: Mouse Heart tissue lysates Lane 2: Mouse Kidney tissue lysates Lane 3: Human U251 cell lysates Lane 4: Human A549 cell lysates Primary: Anti-NCX3 (TMAB-01208) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 100 kDa Observed band size: 100 kDa |
Application | |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Isoform 2 is expressed in brain and skeletal muscle. Isoform 3 is expressed in excitable cells of brain, retina and skeletal muscle. Isoform 4 is expressed in skeletal muscle. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | SLC8A3 is a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. |
Immunogen | KLH conjugated synthetic peptide: human NCX3 |
Antigen Species | Human |
Gene Name | SLC8A3 |
Gene ID | |
Protein Name | Sodium/calcium exchanger 3 |
Uniprot ID | |
Function | Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity). |
Molecular Weight | Theoretical: 100 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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