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Antifection

An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. Antifection includes antibiotics, antifungals, antiprotozoa and antivirals.

Altenuene
TN340129752-43-0
Altenuene is a mycotoxin, it frequently occurs in food and feed items infested by fungi of the genus Alternaria. Altenuene demonstrates moderate activity against Staphylococcus aureus. Altenuene also exhibits cytotoxic activity against lung cancer cell li
  • $829
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Voriconazole
T0120137234-62-9
Voriconazole (UK-109496) is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 [CYP3A].
  • $30
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Deoxylapachol
TN15693568-90-9
Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevispora CBS 509.92. It also can induc
  • $98
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Lariciresinol
TN185327003-73-2
Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel antifungal agent for the treatment of fungal infectious diseases in humans. Dietary lariciresinol
  • $172
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Clitorin
TN151355804-74-5
Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential.
  • $84
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Dehydroabietic acid
TCS17721740-19-8
1. Dehydroabietic acid (Dehydroabietate) (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma triglyceride (TG) , and hepatic TG levels. 3. DAA derivatives displays anti-secretory and anti-pepsin effect in animal models.
  • $35
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Fluconazole
T138886386-73-4
Fluconazole (UK-49858) is a triazole antifungal agent used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.
  • $36
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Hydrangenol
TN4234480-47-7In house
Hydrangenol is a natural product and can be isolated from Hydrangea serrata leaves. Hydrangenol is an antiphotoaging compound with oral activity. Hydrangenol can reduce MMP and inflammatory cytokine expression and increase moisturizing factors and antioxidant genes level, result in preventing wrinkle formation.
  • $139
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Primin
TN210115121-94-5
Primin is a natural product stored in trichomes on the leaves and stems of Primula obconica, exhibiting antimycobacterial and strong antineoplastic actions.
  • $59
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Ganciclovir
T068882410-32-0
Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
  • $51
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beta-Amyrone
TN3500638-97-1
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity.
  • $122
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Colutehydroquinone
TN1521181311-16-0
Colutehydroquinone is an antifungal isoflavonoid from Colutea arborescens.
  • $105
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3-Feruloylquinic acid
TN12621899-29-2
3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.
  • $215
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Clotrimazole
T050623593-75-1
Clotrimazole (FB 5097), an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol.
  • $45
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Magnolioside
TN190520186-29-2
Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CIP 53.154.Magnolioside exhibits significant neuroprotective activities against glutamate-induced toxicity.
  • $89
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Azadirachtin
TN141711141-17-6
Azadirachtin has antifungal activity, used as an insecticide.
  • $98
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(2S)-2'-Methoxykurarinone
TN1215270249-38-2
(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone displays cytotoxic activity against human myeloid leukemia HL-60 cells.
  • $58
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Kaempferol-7,4'-dimethyl ether
TN289815486-33-6
Kaempferol-7,4'-dimethyl ether, isolated from the rhizomes of Zingiber phillipseae, exhibits antioxidant activity against S. aureus and E. coli with MICs of 200 and 225 μg ml, respectively.
  • $89
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Oxiconazole nitrate
T129064211-46-7
Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad-spectrum imidazole derivative with antifungal activity. Likely inhibiting cytochrome P450-dependent demethylation of lanosterol, it prevents ergosterol synthesis, a crucial component of the fungal cell membrane. This disruption of membrane synthesis and integrity alters permeability, promotes loss of essential intracellular components, and inhibits fungal cell growth.
  • $35
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Cefepime Dihydrochloride Monohydrate
T0868123171-59-5
Cefepime Dihydrochloride Monohydrate (Cefepime HCl) is the hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium fungal species with broad-spectrum bactericidal activity.
  • $39
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Neochamaejasmine B
TN197790411-12-4
Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus.
  • $133
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Miconazole
T034422916-47-8
Miconazole (R18134) is an imidazole antifungal agent used both topically and via intravenous infusion.
  • $39
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Econazole
T044427220-47-9
Econazole ((±)-Econazol) is an imidazole derivative that is commonly used as a topical antifungal agent.
  • $39
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Chlorhexidine
T100055-56-1
Chlorhexidine (Rotersept) is a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram-positive bacteria are more negatively charged, they are more sensitive to this agent.
  • $36
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Idoxuridine
T086354-42-2
Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
  • $30
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Chlorhexidine diacetate
T1000L56-95-1
Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
  • $39
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Terconazole
T221367915-31-5
Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements. Terconazole is active against Candida sp.
  • $30
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Cefmenoxime hydrochloride
T119075738-58-8
Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) is a cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, is a potent inhibitor of Enterobacteriaceae, and is highly resistant to hydrolysis by beta-lactamases. The drug has a high rate of efficacy in many types of infection and to date, no severe side effects have been noted.
  • $58
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Desciclovir
T2230484408-37-7
Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.
  • $58
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Carabrone
TN11141748-81-8
Carabrone, a botanical bicyclic sesquiterpenic lactone, is a promising fungicidal agent that can effectively control G. tritici.
  • $106
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Tioconazole
T014665899-73-2
Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements.
  • $45
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Penciclovir
T164339809-25-1
Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the active metabolite, penciclovir triphosphate, which competitively inhibits viral HSV polymerase by blocking deoxyguanosine triphosphate substrate binding. As a result, herpes viral DNA synthesis and replication are selectively inhibited.
  • $30
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(-)-Corynoxidine
TN152757906-85-1
(-)-Corynoxidine is an AChE inhibitor derived from tubers of Stephania succifera. Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus strains in different degrees.
  • $64
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Chlorhexidine dihydrochloride
T11473697-42-5
Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
  • $39
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Ganciclovir sodium
T22337107910-75-8
Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1).
  • $40
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Econazole nitrate
T0444L24169-02-6
Econazole nitrate (NSC-243115) (Spectazole) is an imidazole class antifungal medicine.
  • $30
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1-Docosanol
T0884661-19-8
1-Docosanol (Behenic alcohol) is a saturated 22-carbon aliphatic alcohol with antiviral activity. 1-Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and the herpes simplex virus envelope, thereby preventing viral entry into cells and subsequent viral activity and replication. 1-Docosanol is used topically in the treatment of recurrent herpes simplex labialis episodes and relieves associated pain and may help heal sores faster.
  • $34
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Cletoquine
T108354298-15-1
Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatment.
  • $291
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Sanggenol A
TN2176174423-30-4
Sanggenol A inhibits influenza A viral and pneumococcal neuraminidase, hence functioning as a dual-acting anti-infective agent.
  • $1,110
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GR-95168
T6780095463-56-2In house
GR-95168 ((+)-C-BVDU) is an antiviral compound for the study of herpes simplex virus infections type 1 and type 2.
  • $293 TargetMol
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STING agonist-30
T748092951078-67-2In house
STING agonist-30 is a potent activator of STING-dependent immune responses, demonstrating broad-spectrum antiviral effects against viruses such as HSV (Herpes Simplex Virus), rotavirus, and SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2).
  • $293 TargetMol
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Tivicilovir
T67813103024-93-7In house
Tivicilovir (AM188) is a hepatitis B virus inhibitor. tiviclovir is a guanine-related acyclic 2'-deoxyguanine analogue with anti-herpesvirus activity.
  • $138
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Eprociclovir
T31659145512-85-2In house
Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention of infections with this virus.Eprociclovir has potent anti-herpetic activity against most human herpesviruses.
  • $160
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KIN101
T11760610753-87-2
KIN101 (3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene), an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has antiviral activity against RNA viruses, HCV, and RSV.
  • $29
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Torachrysone-8-O-b-D-glucoside
TN227764032-49-1
Torachrysone-8-O-b-D-glucoside exhibits alpha-glucosidase inhibitory activities and may be utilized for managing type 2 diabetes.
  • $113
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Methyl protogracillin
TJS174854522-53-1
Methyl protogracillin is a natural product from Dioscorea collettii var. hypoglauca with anti-cancer activity.
  • $132
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EBV lytic cycle inducer-1
T77753394668-43-0
EBV lytic cycle inducer-1 is an iron chelate analogue that induces the lytic cycle of EBV.
  • $83
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Cedrelone
TN36161254-85-9
Cedrelone is a citrulline analog and a phenazine biosynthesis-like domain protein (PBLD) activator.Cedrelone induces apoptosis in cancer cells.Cedrelone is a very potent inducer of apoptosis, causing cell cycle arrest.Cedrelone has insecticidal activity, inhibiting the growth of arrowhead venom of P. saucia and inhibiting moulting of the milkweed bug (Oncopeltus fasciatus). Cedrelone has insecticidal activity, inhibiting the growth of P. saucia and inhibiting moulting of the milkweed bug (Oncopeltus fasciatus).Cedrelone has antitumor effects and exhibits significant cytotoxicity against cancer cell lines such as -60, SMMC-7721, A-549, MCF-7, and SW480.Cedrelone is a very potent inducer of apoptosis, causing cell cycle arrest.Cedrelone is a very potent inducer of apoptosis, leading to cell cycle arrest.
  • $698
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