[D-Trp8]-γ-MSH

Name: [D-Trp8]-γ-MSH
Brand: TargetMol
SKU: TP1893
Rating: 4.5 (1 reviews)

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Catalog No. TP1893Cas No. 321351-81-9

[D-Trp8]-γ-MSH is a selective melanocortin 3 (MC3) receptor agonist with IC50 values of 6.7, 340, and 600 nM for human MC3, MC5, and MC4 receptors, respectively. [D-Trp8]-γ-MSH also exhibits anti-inflammatory efficacy.

[D-Trp8]-γ-MSH

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Catalog No. TP1893Cas No. 321351-81-9

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$148	Inquiry	Inquiry

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	1570.79
Formula	C₇₄H₉₉N₂₁O₁₆S
Cas No.	321351-81-9
Smiles	C([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)C(C)C)=O)CCSC)=O)=O)=O)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(NCC(O)=O)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)C=5C=6C(NC5)=CC=CC6
Relative Density.	1.46 g/cm3 (Predicted)
Sequence	Tyr-Val-Met-Gly-His-Phe-Arg-{d-Trp}-Asp-Arg-Phe-Gly
Sequence Short	YVMGHFR-{d-Trp}-DRFG

Storage & Solubility Information

Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O: 1 mg/mL (0.64 mM), Sonication is recommended.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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