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Anti-CD31/PECAM-1 Antibody (5D42) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (5D42) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-CD31/PECAM-1 Antibody (5D42) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (5D42) can be used in IHC-P. |
Alias | platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 5D42 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human CD31 in human placenta with rabbit monoclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human CD31 in human stomach with rabbit monoclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections. |
Application | IHC-P |
Recommended Dose | IHC-P: 1:200-1:800 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD31/PECAM-1 (rh CD31/PECAM-1; EAW94208.1; Met1-Lys601). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human CD31/PECAM-1 Protein |
Antigen Species | Human |
Biology Area | Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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