Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 371.00 | |
500 μg | 5 days | $ 1,490.00 | |
1 mg | 5 days | $ 2,480.00 |
Description | Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
Species | Human |
Expression System | HEK293 |
Tag | C-His-Avi |
Accession Number | AAH17865 |
Synonyms | CD16, FcRIII, IMD20, IGFR3, FCG3, Fc γ RIIIA, CD16A, FCGR3, FcRIIIa, FCGR3A, FcgRIIIA, FCGRIII, Fc γ RIIIA/CD16a (V176), FcR-10, Fc gamma RIIIA |
Construction | Recombinant Human Fc gamma RIIIA/CD16a (V176) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Gly17-Gln208(V176).[Accession |AAH17865] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 24.7 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
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Please read the User Guide of Recombinant Proteins for more specific information.
Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi) IGFR-3 IMD 20 CD16 FcRIII IMD20 CD 16 IGFR3 FCG3 Fc γ RIIIA FCG-3 CD-16 CD16A FCGR-3 FCGR3 IGFR 3 FcRIIIa IMD-20 FCGR3A FCGR 3 FCG 3 FcgRIIIA FCGRIII Fc γ RIIIA/CD16a (V176) FcR-10 Fc gamma RIIIA recombinant recombinant-proteins proteins protein