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Anti-EMMPRIN/CD147 Antibody is a humanized monoclonal antibody targeting CD147 (also known as Basigin or EMMPRIN). This product binds specifically to CD147, blocking its interaction with pathogen proteins (such as the spike protein S of SARS-CoV-2). As CD147 is a key receptor for viral entry into host cells, the antibody effectively inhibits the infection of susceptible cells by competitively binding to the extracellular domain of CD147.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
| Description | Anti-EMMPRIN/CD147 Antibody is a humanized monoclonal antibody targeting CD147 (also known as Basigin or EMMPRIN). This product binds specifically to CD147, blocking its interaction with pathogen proteins (such as the spike protein S of SARS-CoV-2). As CD147 is a key receptor for viral entry into host cells, the antibody effectively inhibits the infection of susceptible cells by competitively binding to the extracellular domain of CD147. |
| In vitro | In biochemical and cell-based assays, Anti-EMMPRIN/CD147 Antibody binds with high affinity to the extracellular domain of CD147 and competitively blocks the binding of the SARS-CoV-2 spike protein; in viral infection assays using Vero E6 cells, the antibody exhibits potent neutralizing activity, significantly inhibiting viral entry and replication in a concentration-dependent manner [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | EMMPRIN/CD147 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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