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Anti-EMMPRIN/CD147 Antibody is a humanized monoclonal antibody against CD147(Basigin), which can specifically bind to CD147 and block its interaction with pathogen proteins. Because CD147 is one of the key receptors for virus to invade host cells, Anti-EMMPRIN/CD147 Antibody can effectively inhibit the infection process of virus to susceptible cells by competitively binding to the extracellular domain of CD147.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
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| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
| Description | Anti-EMMPRIN/CD147 Antibody is a humanized monoclonal antibody against CD147(Basigin), which can specifically bind to CD147 and block its interaction with pathogen proteins. Because CD147 is one of the key receptors for virus to invade host cells, Anti-EMMPRIN/CD147 Antibody can effectively inhibit the infection process of virus to susceptible cells by competitively binding to the extracellular domain of CD147. |
| In vitro | In biochemical and cell-based assays, Anti-EMMPRIN/CD147 Antibody binds with high affinity to the extracellular domain of CD147 and competitively blocks the binding of the SARS-CoV-2 spike protein; in viral infection assays using Vero E6 cells, the antibody exhibits potent neutralizing activity, significantly inhibiting viral entry and replication in a concentration-dependent manner [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | EMMPRIN/CD147 |
| Isotype | IgG1 |
| Storage | Store at -20°C Shipping with blue ice. |
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