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Anti-NPPB Antibody (6G519)

😃Good
Catalog No. TMAH-00823
Alias γ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP

Anti-NPPB Antibody (6G519) is a Mouse antibody targeting NPPB. Anti-NPPB Antibody (6G519) can be used in ELISA, IHC.

Anti-NPPB Antibody (6G519)

Anti-NPPB Antibody (6G519)

😃Good
Catalog No. TMAH-00823Alias γ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP
Anti-NPPB Antibody (6G519) is a Mouse antibody targeting NPPB. Anti-NPPB Antibody (6G519) can be used in ELISA, IHC.
Pack SizePriceAvailabilityQuantity
50 μg$209 7-10 days
100 μg$349 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Mouse Monoclonal

Application: ELISA, IHC

Reactivity: Human
Aliasγ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP
Ig Type
IgG2b
Clone
6G519
Reactivity
Human
Verified Activity
1. Immunohistochemistry of paraffin-embedded human brain using TMAH-00823 in 30μg/ml dilute concentrations.
2. Immunohistochemistry of paraffin-embedded human heart using TMAH-00823 in 30μg/ml dilute concentrations.
3. Immunohistochemistry of paraffin-embedded human brain using TMAH-00823 in 30μg/ml dilute concentrations.
4. Immunohistochemistry of paraffin-embedded human heart using TMAH-00823 in 30μg/ml dilute concentrations.
Application
ELISA, IHC
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular Localization[NT-proBNP]: Secreted.; [proBNP(3-108)]: Secreted.; [Brain natriuretic peptide 32]: Secreted.; [BNP(3-32)]: Secreted.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Purity>95%
Research BackgroundCardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3. May affect cardio-renal homeostasis. Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32. May have a role in cardio-renal homeostasis. Able to promote the production of cGMP.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human NPPB Protein
Antigen Species
Human
Gene ID
4879
Uniprot ID
Biology Area
Signal Transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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