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Anti-NPPB Antibody (6G519) (Synonyms: γ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain ...)

Catalog No. TMAH-00823 Copy Product Info
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Anti-NPPB Antibody (6G519) is a Mouse antibody targeting NPPB. Anti-NPPB Antibody (6G519) can be used in ELISA,IHC.

Anti-NPPB Antibody (6G519)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00823
Synonyms γ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP

Anti-NPPB Antibody (6G519) is a Mouse antibody targeting NPPB. Anti-NPPB Antibody (6G519) can be used in ELISA,IHC.

Anti-NPPB Antibody
(6G519)
Pack SizePriceUSA StockGlobal StockQuantity
50 μg$2097-10 days7-10 days
100 μg$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NPPB Antibody (6G519) is a Mouse antibody targeting NPPB. Anti-NPPB Antibody (6G519) can be used in ELISA,IHC.
Synonymsγ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP
Ig Type
IgG2b
Clone
6G519
Reactivity
Human
Verified Activity
1. Immunohistochemistry of paraffin-embedded human brain using TMAH-00823 in 30μg/ml dilute concentrations.
2. Immunohistochemistry of paraffin-embedded human heart using TMAH-00823 in 30μg/ml dilute concentrations.
3. Immunohistochemistry of paraffin-embedded human brain using TMAH-00823 in 30μg/ml dilute concentrations.
4. Immunohistochemistry of paraffin-embedded human heart using TMAH-00823 in 30μg/ml dilute concentrations.
Application
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular Localization[NT-proBNP]: Secreted.; [proBNP(3-108)]: Secreted.; [Brain natriuretic peptide 32]: Secreted.; [BNP(3-32)]: Secreted.
Tissue Specificity[Brain natriuretic peptide 32]: Detected in the cardiac atria (at protein level). Detected in the kidney distal tubular cells (at protein level).
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Purity>95%
Research BackgroundCardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3. May affect cardio-renal homeostasis. Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32. May have a role in cardio-renal homeostasis. Able to promote the production of cGMP.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human NPPB Protein
Antigen Species
Human
Gene Name
NPPB
Gene ID
Uniprot ID
Biology Area
Signal Transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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