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Corticotropin-releasing factor (human) (acetate)

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Catalog No. T37111

Human CRF acetate is a chemical compound that effectively stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.

Corticotropin-releasing factor (human) (acetate)
Other Forms of Corticotropin-releasing factor (human) (acetate):

Corticotropin-releasing factor (human) (acetate)

😃Good
Catalog No. T37111
Human CRF acetate is a chemical compound that effectively stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
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1 mg$276Backorder
5 mg$741Backorder
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Product Introduction

Bioactivity
Description
Human CRF acetate is a chemical compound that effectively stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
In vitro
CRF enhances the excitability of type II dlBNST neurons via the activation of the AC-cAMP-PKA pathway, leading to pain-induced aversive responses[1].
In vivo
In rats that received an injection of CRF (1 nmol/side), the duration spent in the drug-paired compartment during the test session (314±22 s) was significantly reduced compared to the time spent in the same compartment during the preconditioning session (520±18 s)[1].
Chemical Properties
Relative Density.no data available
SequenceH-DL-Ser-DL-Glu-DL-Glu-DL-Pro-DL-Pro-DL-xiIle-DL-Ser-DL-Leu-DL-Asp-DL-Leu-DL-xiThr-DL-Phe-DL-His-DL-Leu-DL-Leu-DL-Arg-DL-Glu-DL-Val-DL-Leu-DL-Glu-DL-Met-DL-Ala-DL-Arg-DL-Ala-DL-Glu-DL-Gln-DL-Leu-DL-Ala-DL-Gln-DL-Gln-DL-Ala-DL-His-DL-Ser-DL-Asn-DL-Arg-DL-L
Sequence ShortSEEPPXSLDLXFHLLREVLEMARAEQLAQQAHSNRKLMEXX
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

Corticotropin-releasing factorCorticotropin releasing factor (human) (acetate)Corticotropinreleasing factor (human) (acetate)
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