Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) compound. VP-4604 exhibited significant microbial growth inhibition against S. aureus with an MIC of 4-8 μg/mL. VP-4604 inhibited the growth of methicillin-resistant S. aureus with a growth inhibition rate of over 95%.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 30.00 | |
100 mg | In stock | $ 39.00 | |
500 mg | In stock | $ 91.00 |
Description | VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) compound. VP-4604 exhibited significant microbial growth inhibition against S. aureus with an MIC of 4-8 μg/mL. VP-4604 inhibited the growth of methicillin-resistant S. aureus with a growth inhibition rate of over 95%. |
Targets&IC50 | S. aureus:4-8 µg/mL(MIC) |
In vitro |
VP-4604 (2.5 mM) showed low toxicity towards mammalian cells and was tolerated by mammalian cells (HaCaT, lymphocytes) with inhibition growth (%) of 44.1% and >50%, respectively.[1] VP-4604 (2.5 mM, 18 h) inhibits drug-resistant S. aureus and P. aeruginosa with growth inhibition (%) GI >95% [1]. VP-4604 shows low cytotoxicity with a CC 50 value >118.4 mM towards HEK-293 (human embryonic kidney) ATCC CRL‐1573 and an HC 10 vaule >118.4 μM towards RBC (human red blood cells).[1] |
Synonyms | 1-((4-Nitrophenyl)sulfonyl)piperidine |
Molecular Weight | 270.3 |
Formula | C11H14N2O4S |
CAS No. | 64268-93-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (83.2 mM ), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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VP-4604 64268-93-5 VP4604 1-((4-Nitrophenyl)sulfonyl)piperidine VP 4604 inhibitor inhibit