Shopping Cart

Your shopping cart is currently empty

VP-4604

Name: VP-4604
Brand: TargetMol
SKU: T64316
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T64316Cas No. 64268-93-5

Alias 1-((4-Nitrophenyl)sulfonyl)piperidine

VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) compound that exhibited significant microbial growth inhibition against S. aureus with an MIC of 4-8 μg/mL and a growth inhibition rate of over 95%.

VP-4604

Copy Product Info

😃Good

Purity: 99.75%

Catalog No. T64316Alias 1-((4-Nitrophenyl)sulfonyl)piperidineCas No. 64268-93-5

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$29	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.75%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) compound that exhibited significant microbial growth inhibition against S. aureus with an MIC of 4-8 μg/mL and a growth inhibition rate of over 95%.
Targets&IC50	S. aureus:4-8 µg/mL(MIC)
In vitro	VP-4604 (2.5 mM) showed low toxicity towards mammalian cells and was tolerated by mammalian cells (HaCaT, lymphocytes) with inhibition growth (%) of 44.1% and >50%, respectively.[1] VP-4604 (2.5 mM, 18 h) inhibits drug-resistant S. aureus and P. aeruginosa with growth inhibition (%) GI >95% [1]. VP-4604 shows low cytotoxicity with a CC 50 value >118.4 mM towards HEK-293 (human embryonic kidney) ATCC CRL‐1573 and an HC 10 vaule >118.4 μM towards RBC (human red blood cells).[1]
Synonyms	1-((4-Nitrophenyl)sulfonyl)piperidine

Chemical Properties

Molecular Weight	270.3
Formula	C₁₁H₁₄N₂O₄S
Cas No.	64268-93-5
Smiles	[O-][N+](=O)c1ccc(cc1)S(=O)(=O)N1CCCCC1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 6 mg/mL (22.2 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6996 mL	18.4980 mL	36.9959 mL	184.9797 mL
5 mM	0.7399 mL	3.6996 mL	7.3992 mL	36.9959 mL
10 mM	0.3700 mL	1.8498 mL	3.6996 mL	18.4980 mL
20 mM	0.1850 mL	0.9249 mL	1.8498 mL	9.2490 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc