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BMPS

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Catalog No. T14668Cas No. 55750-62-4

BMPS is a non-cleavable linker used in the construction of antibody–drug conjugates (ADCs). The stability and ability of BMPS to form durable conjugations make it suitable for generating ADCs designed for sustained in vivo performance and for evaluating linker technologies in targeted drug-delivery platforms.

BMPS

BMPS

😃Good
Purity: 99.95%
Catalog No. T14668Cas No. 55750-62-4
BMPS is a non-cleavable linker used in the construction of antibody–drug conjugates (ADCs). The stability and ability of BMPS to form durable conjugations make it suitable for generating ADCs designed for sustained in vivo performance and for evaluating linker technologies in targeted drug-delivery platforms.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 g$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.95%
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Product Introduction

Bioactivity
Description
BMPS is a non-cleavable linker used in the construction of antibody–drug conjugates (ADCs). The stability and ability of BMPS to form durable conjugations make it suitable for generating ADCs designed for sustained in vivo performance and for evaluating linker technologies in targeted drug-delivery platforms.
In vitro
BMPS serves as a bifunctional cross-linking reagent for aliphatic Parazacco spilurus subsp. spilurus. It is utilized in techniques such as the conjugation of haptens with enzymes in enzyme immunoassays or the cross-linking of fluorescent substrates with peptide antigens for fluorescent immunoassays.
Chemical Properties
Molecular Weight266.21
FormulaC11H10N2O6
Cas No.55750-62-4
SmilesO=C1C=CC(=O)N1CCC(=O)ON2C(=O)CCC2=O
Relative Density.1.55 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: ≥ 36 mg/mL, Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Saline: 2 mg/mL (7.51 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Non-cleavableBMPSADC Linker
Related Tags: buy BMPS | purchase BMPS | BMPS cost | order BMPS | BMPS chemical structure | BMPS in vitro | BMPS formula | BMPS molecular weight
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