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Anti-BPI Antibody (8S152) is a Mouse antibody targeting BPI. Anti-BPI Antibody (8S152) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | 189 € | 7-10 days |
Description | Anti-BPI Antibody (8S152) is a Mouse antibody targeting BPI. Anti-BPI Antibody (8S152) can be used in ELISA. |
Alias | rBPI, BPIFD1, bactericidal/permeability-increasing protein |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 8S152 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BPI (rh BPI; TMPY-02908; P17213; Met1-Lys487). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Bactericidal/permeability-increasing protein is a member of the BPI/LBP/Plunc superfamily and BPI/LBP family. It is a cationic protein which can be detected in the azurophilic granule and on the surface of polymorphonuclear leukocytes. Bactericidal/permeability-increasing protein also is a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. Bactericidal/permeability-increasing protein contains two domains that adopt the same structural fold, even though they have little sequence similarity. It binds to and neutralises lipopolysaccharides from the outer membrane of Gram-negative bacteria. The cytotoxic action of bactericidal/permeability-increasing protein is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human BPI Protein (TMPY-02908) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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