IL-6 Protein, Rat, Recombinant (HEK293)

Name: IL-6 Protein, Rat, Recombinant (HEK293)
Brand: TargetMol
SKU: TMPS-00088
Rating: 4.5 (1 reviews)

(Synonyms: MGI-2, IL6, IFN-β2, IFN-b2, HSF, HPGF, BSF-2, BCDF, B cell differentiation factor, 26 kDa protein) Copy Product Info

Synonyms: MGI-2, IL6, IFN-β2, IFN-b2, HSF, HPGF, BSF-2, BCDF, B cell differentiation factor, 26 kDa protein

Catalog No. TMPS-00088 Copy Product Info

IL-6 Protein, Rat, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is P20607-1.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$138	7-10 days	7-10 days
10 µg	$197	7-10 days	7-10 days
25 µg	$339	7-10 days	7-10 days
50 µg	$553	7-10 days	7-10 days
100 µg	$888	7-10 days	7-10 days
200 µg	$1,490	7-10 days	7-10 days
500 µg	$2,880	7-10 days	7-10 days
1 mg	$4,750	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 3.0 pg/ml, measured by a cell proliferation assay using 7TD1 Cells.
Description	IL-6 Protein, Rat, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is P20607-1.
Species	Rat
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	P20607-1
Construction	Phe25-Thr211
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	MGI-2, IL6, IFN-β2, IFN-b2, HSF, HPGF, BSF-2, BCDF, B cell differentiation factor, 26 kDa protein
Research Background	Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, and nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction and released into the blood stream to help break down fats and improve insulin resistance.

Chemical Properties

Molecular Weight

21~26 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.