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Anti-CIDEC Polyclonal Antibody
(Synonyms: FSP27, FLJ20871, Fat-specific protein FSP27 homolog, Fat specific protein 27, CIDEC, CIDE3, CIDE C, CIDE 3, Cell death-inducing DFFA-like effector protein C, Cell Death Inducing DFFA Like Effector C, Cell death activator CIDE-3, Cell Death Activator) Copy Product Info
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Synonyms: FSP27, FLJ20871, Fat-specific protein FSP27 homolog, Fat specific protein 27, CIDEC, CIDE3, CIDE C, CIDE 3, Cell death-inducing DFFA-like effector protein C, Cell Death Inducing DFFA Like Effector C, Cell death activator CIDE-3, Cell Death Activator
Catalog No. TMAB-00432 Copy Product Info
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Anti-CIDEC Polyclonal Antibody is a Rabbit antibody targeting CIDEC. Anti-CIDEC Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-CIDEC Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-CIDEC Polyclonal Antibody is a Rabbit antibody targeting CIDEC. Anti-CIDEC Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | FSP27, FLJ20871, Fat-specific protein FSP27 homolog, Fat specific protein 27, CIDEC, CIDE3, CIDE C, CIDE 3, Cell death-inducing DFFA-like effector protein C, Cell Death Inducing DFFA Like Effector C, Cell death activator CIDE-3, Cell Death Activator |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Pig) |
| Application | |
| Recommended Dose | FCM=1 μg/Test; ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus (By similarity). Endoplasmicreticulum (By similarity). Lipid droplet. Note=Diffuses quickly onlipid droplet surface, but becomes trapped and clustered at lipiddroplet contact sites, thereby enabling its rapid enrichment atlipid droplet contact sites. |
| Tissue Specificity | Expressed mainly in adipose tissue, smallintestine, heart, colon and stomach and, at lower levels, in brain,kidney and liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]. Tissue specificity: Expressed mainly in small intestine, heart, colon and stomach and, at lower levels, in brain, kidney and liver. |
| Immunogen | KLH conjugated synthetic peptide: human CIDEC |
| Antigen Species | Human |
| Gene Name | CIDEC |
| Gene ID | |
| Protein Name | Cell death activator CIDE-3 |
| Uniprot ID | |
| Function | May act as a CEBPB coactivator in white adipose tissueto control the expression of a subset of CEBPB downstream targetgenes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH (Bysimilarity). Binds to lipid droplets and regulates theirenlargement, thereby restricting lipolysis and favoring storage. Atfocal contact sites between lipid droplets, promotes directionalnet neutral lipid transfer from the smaller to larger lipiddroplets. The transfer direction may be driven by the internalpressure difference between the contacting lipid droplet pair. Whenoverexpressed in preadipocytes, induces apoptosis or increases cellsusceptibility to apoptosis induced by serum deprivation or TGFBtreatment. As mature adipocytes, that express high CIDEC levels,are quite resistant to apoptotic stimuli, the physiologicalsignificance of its role in apoptosis is unclear. |
| Molecular Weight | Theoretical: 27 kDa. Actual: 27 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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