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Anti-Cathepsin A Antibody (1N273) (Synonyms: Ppgb, PPCA, cathepsin A, AU019505)

Catalog No. TMAY-03246 Copy Product Info
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Anti-Cathepsin A Antibody (1N273) is a Rabbit antibody targeting Cathepsin A. Anti-Cathepsin A Antibody (1N273) can be used in ELISA.

Anti-Cathepsin A Antibody (1N273)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03246
Synonyms Ppgb, PPCA, cathepsin A, AU019505

Anti-Cathepsin A Antibody (1N273) is a Rabbit antibody targeting Cathepsin A. Anti-Cathepsin A Antibody (1N273) can be used in ELISA.

Anti-Cathepsin A Antibody
(1N273)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Cathepsin A Antibody (1N273) is a Rabbit antibody targeting Cathepsin A. Anti-Cathepsin A Antibody (1N273) can be used in ELISA.
SynonymsPpgb, PPCA, cathepsin A, AU019505
Ig Type
Rabbit IgG
Clone
1N273
Reactivity
Mouse
Specificity
Mouse Cathepsin A
No cross-reactivity in ELISA with
Human CTSA
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Cathepsin A / CTSA (TMPY-01450; P16675-1; Met1-Tyr474).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLysosomal carboxypeptidase, cathepsin A (protective protein, CathA), is a component of the lysosomal multienzyme complex along with beta-galactosidase (GAL) and sialidase Neu1, where it activates Neu1 and protects GAL and Neu1 against the rapid proteolytic degradation. Cathepsin A is a multicatalytic enzyme with deamidase and esterase in addition to carboxypeptidase activities. It was recently identified in human platelets as deamidase. In vitro, it hydrolyzes a variety of bioactive peptide hormones including tachykinins, suggesting that extralysosomal cathepsin A plays a role in regulation of bioactive peptide functions. It is a member of the alpha/beta hydrolase fold family and has been suggested to share a common ancestral relationship with other alpha/beta hydrolase fold enzymes, such as cholinesterases. Cathepsin A defects are linked to multiple forms of Galactosialidosis with a combined secondary deficiency of beta-galactosidase and neuraminidase. Cathepsin A is a key molecule in the onset of galactosialidosis and also highlight the therapeutic acts in vivo as an endothelin-1-inactivating enzyme and strongly confirm a crucial role of this enzyme in effective elastic fiber formation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse Cathepsin A / CTSA protein (TMPY-01450)
Antigen Species
Mouse
Biology Area
Serine Proteases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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