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Anti-Cathepsin A Antibody (1N273)
😃Good
Catalog No. TMAY-03246
Alias Ppgb, PPCA, cathepsin A, AU019505
Anti-Cathepsin A Antibody (1N273) is a Rabbit antibody targeting Cathepsin A. Anti-Cathepsin A Antibody (1N273) can be used in ELISA.
Anti-Cathepsin A Antibody (1N273)
Anti-Cathepsin A Antibody (1N273)
😃Good
Catalog No. TMAY-03246Alias Ppgb, PPCA, cathepsin A, AU019505
Anti-Cathepsin A Antibody (1N273) is a Rabbit antibody targeting Cathepsin A. Anti-Cathepsin A Antibody (1N273) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Cathepsin A Antibody (1N273) is a Rabbit antibody targeting Cathepsin A. Anti-Cathepsin A Antibody (1N273) can be used in ELISA. |
| Alias | Ppgb, PPCA, cathepsin A, AU019505 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1N273 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Cathepsin A / CTSA (TMPY-01450; P16675-1; Met1-Tyr474). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Lysosomal carboxypeptidase, cathepsin A (protective protein, CathA), is a component of the lysosomal multienzyme complex along with beta-galactosidase (GAL) and sialidase Neu1, where it activates Neu1 and protects GAL and Neu1 against the rapid proteolytic degradation. Cathepsin A is a multicatalytic enzyme with deamidase and esterase in addition to carboxypeptidase activities. It was recently identified in human platelets as deamidase. In vitro, it hydrolyzes a variety of bioactive peptide hormones including tachykinins, suggesting that extralysosomal cathepsin A plays a role in regulation of bioactive peptide functions. It is a member of the alpha/beta hydrolase fold family and has been suggested to share a common ancestral relationship with other alpha/beta hydrolase fold enzymes, such as cholinesterases. Cathepsin A defects are linked to multiple forms of Galactosialidosis with a combined secondary deficiency of beta-galactosidase and neuraminidase. Cathepsin A is a key molecule in the onset of galactosialidosis and also highlight the therapeutic acts in vivo as an endothelin-1-inactivating enzyme and strongly confirm a crucial role of this enzyme in effective elastic fiber formation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse Cathepsin A / CTSA protein (TMPY-01450) |
| Antigen Species | Mouse |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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